Interventional radiology in liver transplantation

Nikhil B. Amesur, Albert B. Zajko – 23 February 2006 – Improvements in surgical technique, advances in the field of immunosuppresion and the early diagnosis and treatment of complications related to liver transplantation have all led to prolonged survival after liver transplantation. In particular, advances in diagnostic and interventional radiology have allowed the Interventional Radiologist, as part of the transplant team, to intervene early in patients presenting with complications related to organ transplant with resultant increase in graft and patient survival.

Regional sharing for adult status 1 candidates: Reduction in waitlist mortality

Kenneth Washburn, Ann Harper, Goran Klintmalm, John Goss, Glenn Halff – 23 February 2006 – The intent of regional sharing for status 1 candidates is to promote timely access to donor livers. Presumably this decreases waitlist mortality. Little published data exists that supports this policy. Organ Procurement and Transplantation Network data was used to calculate region 4 and national adult waitlist death and transplant rates 4 yr prior to (period A) and after (period B) implementation of the sharing agreement in July 1999.

Characterization of human liver dendritic cells in liver grafts and perfusates

Brenda M. Bosma, Herold J. Metselaar, Shanta Mancham, Partrick P.C. Boor, Johannes G. Kusters, Geert Kazemier, Hugo W. Tilanus, Ernst J. Kuipers, Jaap Kwekkeboom – 23 February 2006 – It is generally accepted that donor myeloid dendritic cells (MDC) are the main instigators of acute rejection after organ transplantation. The aim of the present study was to characterize MDC in human donor livers using liver grafts and perfusates as a source. Perfusates were collected during ex vivo vascular perfusion of liver grafts pretransplantation.

Split and whole liver transplantation outcomes: A comparative cohort study

Massimo Cardillo, Nicola De Fazio, Paola Pedotti, Tullia De Feo, Luigi Rainero Fassati, Vincenzo Mazzaferro, Michele Colledan, Bruno Gridelli, Lucio Caccamo, Luciano DeCarlis, Umberto Valente, Enzo Andorno, Mariangelo Cossolini, Cristiano Martini, Adelmo Antonucci, Umberto Cillo, Giacomo Zanus, Umberto Baccarani, Mario Scalamogna, NITp Liver Transplantation Working Group – 23 February 2006 – A specific split liver transplantation (SLT) program has been pursued in the North Italian Transplant program (NITp) since November 1997.

Percutaneous transluminal angioplasty for hepatic artery stenosis after living donor liver transplantation

Yoshihisa Kodama, Yusuke Sakuhara, Daisuke Abo, Tsuyoshi Shimamura, Hiroyuki Furukawa, Satoru Todo, Kazuo Miyasaka – 23 February 2006 – The purpose of this study was to evaluate the efficacy of percutaneous transluminal angioplasty (PTA) for treatment of hepatic artery stenosis after living donor liver transplantation. Eighteen patients with hepatic artery stenosis after living donor liver transplantation were included in this study. The success rate and complications of PTA and recurrent stenosis of the hepatic artery were evaluated.

“Hepar divisum”– as a rare donor complication after intraoperative mortality of the recipient of an intended living donor liver transplantation

Silvio Nadalin, Massimo Malagó, Giuliano Testa, Randolph Schaffer, Georgios C. Sotiropoulos, Andrea Frilling, Christoph E. Broelsch – 23 February 2006 – In this study, we present our experience with 4 healthy donors having the rare condition of “hepar divisum” after the intraoperative death of the recipient of an intended right adult living donor liver transplantation (LDLT). The study included 4 donors and 4 intended right LDLT recipients affected by neuroendocrine tumor (n = 2), hepatocellular carcinoma (n = 1), and cryptogenic cirrhosis (n = 1). All 4 recipients died intraoperatively.

Caroli's disease and orthotopic liver transplantation

Shahid Habib, Obaid Shakil, Osvaldo F. Couto, Anthony J. Demetris, John J. Fung, Amadeo Marcos, Kapil Chopra – 23 February 2006 – Caroli's disease is a rare congenital hepatic disease, characterized by segmental dilatation of the biliary tree. Patients who have recurrent bouts of biliary infection, particularly those with complications related to portal hypertension, may require orthotopic liver transplantation (OLT). Few case reports have described the outcome of OLT in patients with Caroli's disease and to date there is no large series reported in the literature.

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