Liver transplantation for Wilson's disease: The burden of neurological and psychiatric disorders

Valentina Medici, Vincenzo G. Mirante, Luigi R. Fassati, Maurizio Pompili, Domenico Forti, Massimo Del Gaudio, Carlo P. Trevisan, Umberto Cillo, Giacomo C. Sturniolo, Stefano Fagiuoli – 25 August 2005 – A retrospective data analysis on liver transplantation for Wilson's disease (WD) was performed among Italian Liver Transplant Centers. Thirty‐seven cases were identified. The main indication for liver transplantation was chronic advanced liver disease in 78% of patients. Mixed hepatic and neuropsychiatric symptoms were recorded in 32.3%.

Use of yttrium‐90 microspheres (TheraSphere®) in a patient with unresectable hepatocellular carcinoma leading to liver transplantation: A case report

Laura M. Kulik, Mary F. Mulcahy, Russell D. Hunter, Albert A. Nemcek, Michael M. Abecassis, Riad Salem – 25 August 2005 – Prior to therapy, model for end stage liver disease (MELD) scoring, diagnostic imaging and tumor staging were performed in a patient with T3 HCC. The patient received an orthotopic liver transplant (OLT) 42 days after treatment. The explant specimen showed complete necrosis of the target tumor. Follow‐up of this patient has demonstrated no evidence of recurrence. There was no life threatening or fatal adverse experiences related to treatment.

Evaluation of renal function in liver transplant recipients receiving daclizumab (Zenapax), mycophenolate mofetil, and a delayed, low‐dose tacrolimus regimen vs. a standard‐dose tacrolimus and mycophenolate mofetil regimen: A multicenter randomized clinic

Eric M. Yoshida, Paul J. Marotta, Paul D. Greig, Norman M. Kneteman, Denis Marleau, Marcelo Cantarovich, Kevork M. Peltekian, Leslie B. Lilly, Charles H. Scudamore, Vincent G. Bain, William J. Wall, Andre Roy, Robert F. Balshaw, Jeffrey S.T. Barkun – 25 August 2005 – Posttransplant chronic renal failure, secondary to calcineurin inhibitor agents, is emerging as a major problem in liver transplantation.

Overcoming the portal steal phenomenon in auxiliary partial orthotopic liver transplantation by modulation of the venous outflow of the native liver

Dieter C. Broering, Jessica Walter, Atef F. Bassas – 25 August 2005 – The main drawback of auxiliary partial orthotopic liver transplantation (APOLT) is the competition of the portal flow between the graft and the native liver, leading to graft failure. In two patients with Crigler‐Najjar syndrome type I, the intrahepatic resistance of the native liver was increased by occluding the recipients middle hepatic vein during parenchymal transection, leading the portal flow towards the graft. This new surgical technique could encourage centers to recommence APOLT.

Emergency splenic arterial embolization for massive variceal bleeding in liver recipient with left‐sided portal hypertension

Hsin‐You Ou, Tung‐Liang Huang, Tai‐Yi Chen, Leo Leung‐Chit Tsang, Allan M. Concejero, Chao‐Long Chen, Yu‐Fan Cheng – 25 August 2005 – Splenic vein thrombosis with gastric variceal bleeding is difficult to manage, and splenectomy may be necessary to stop variceal bleeding. The authors report the case of a post–orthotopic liver transplant patient with bleeding gastric varices secondary to splenic vein thrombosis treated by partial splenic artery embolization.

Risk factors for Staphylococcus aureus infection in liver transplant recipients

Frédéric Bert, Claire Bellier, Ludovic Lassel, Valérie Lefranc, François Durand, Jacques Belghiti, France Mentré, Bruno Fantin – 25 August 2005 – Staphylococcus aureus is the leading cause of bacterial infection in liver transplant recipients. Preoperative nasal carriage of methicillin‐resistant S. aureus (MRSA) is associated with a high risk of infection. We conducted a retrospective cohort study in order to identify independent risk factors for early‐onset S. aureus infection after liver transplantation. Patients were screened preoperatively for methicillin‐susceptible S.

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