Hanh‐Tu Lieu, Frédéric Batteux, Marie‐Thérèse Simon, Alexandre Cortes, Carole Nicco, Flora Zavala, Alain Pauloin, José Guilherme Tralhao, Olivier Soubrane, Bernard Weill, Christian Bréchot, Laurence Christa – 22 August 2005 – Human hepatocarcinoma‐intestine‐pancreas/pancreatic‐associated protein HIP/PAP is a secreted C‐type lectin belonging to group VII, according to Drickamer's classification. HIP/PAP is overexpressed in liver carcinoma; however, its functional role remains unclear.

Akira Anan, Gregory J. Gores – 22 August 2005

Jorge A. Marrero, Robert J. Fontana, Grace L. Su, Hari S. Conjeevaram, Anna S. Lok – 22 August 2005

Zobair M. Younossi, Ancha Baranova, Katharine Ziegler, Luca Del Giacco, Karen Schlauch, Timothy L. Born, Hazem Elariny, Francesco Gorreta, Amy VanMeter, Abraham Younoszai, Janus P. Ong, Zachary Goodman, Vikas Chandhoke – 22 August 2005 – Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and some of its forms are progressive. This study describes the profiling of hepatic gene expression and serum protein content in patients with different subtypes of NAFLD.

Loïc Sentilhes, Eric Verspyck, Horace Roman, Loïc Marpeau – 22 August 2005

Karla J. Helbig, Daryl T.‐Y. Lau, Ljiljana Semendric, Hugh A. J. Harley, Michael R. Beard – 17 August 2005 – Interferon (IFN) α inhibits hepatitis C virus (HCV) replication both clinically and in vitro; however, the complete spectrum of interferon‐stimulated genes (ISGs) expressed in the HCV‐infected liver or the genes responsible for control of HCV replication have not been defined. To better define ISG expression in the chronically infected HCV liver, DNA microarray analysis was performed on 9 individuals with chronic hepatitis C (CHC).

Mical S. Campbell, Colleen M. Brensinger, Arun J. Sanyal, Chris Gennings, Florence Wong, Kris V. Kowdley, Timothy McCashland, K. Rajender Reddy – 17 August 2005 – Uncontrolled studies suggest that transjugular intrahepatic portal‐systemic shunting (TIPS) may improve quality of life in patients with refractory ascites. We hypothesized that any improvement of quality of life in patients with TIPS would be matched in controls due to the competing effects of improved ascites and worsened hepatic encephalopathy.

Stefano Fiorucci, Elisabetta Antonelli, Andrea Mencarelli, Stefano Orlandi, Barbara Renga, Giovanni Rizzo, Eleonora Distrutti, Vijay Shah, Antonio Morelli – 17 August 2005 – The regulation of sinusoidal resistance is dependent on the contraction of hepatic stellate cells (HSC) around sinusoidal endothelial cell (SEC) through paracrine cross‐talk of vasoconstrictor and vasodilator agents. Hydrogen sulfide (H2S), a recently discovered gas neurotransmitter, is a putative vasodilator whose role in hepatic vascular regulation and portal hypertension is unexplored.

Zsolt Sarang, Péter Molnár, Tamás Németh, Szabolcs Gomba, Tamás Kardon, Gerry Melino, Susanna Cotecchia, László Fésüs, Zsuzsa Szondy – 17 August 2005 – Tissue transglutaminase (TG2) is a protein cross‐linking enzyme known to be expressed by hepatocytes and to be induced during the in vivo hepatic apoptosis program. TG2 is also a G protein that mediates intracellular signaling by the alpha‐1b‐adrenergic receptor (AR) in liver cells.

Renato Costi, Vincenzo Violi, Luigi Roncoroni, Leopoldo Sarli – 17 August 2005