Liver Transplantation (LT) is the treatment of choice for patients with decompensated cirrhosis, acute liver failure, small hepatocellular carcinomas (HCCs), or acute liver failure.

Access to liver transplants (LT) has profoundly altered the management of advanced liver disease.

Hepatocellular Carcinoma (HCC) is now the fifth-most common cancer in the world and the third cause of cancer-related mortality as estimated by the World Health Organization.

AASLD develops evidence-based practice guidelines which are updated regularly by a multi-disciplinary panel of experts, including hepatologists, and include recommendations of preferred approaches to the diagnostic, therapeutic, and preventive aspects of care. AASLD also provides practice tools to assist with learning and implementing the new recommendations. 

Hepatic encephalopathy (HE) is a frequent complication and one of the most debilitating manifestations of liver disease, severely affecting the lives of patients and their caregivers.

Hereditary hemochromatosis (HH) remains the most common, identified, genetic disorder in Caucasians.

Michael Schonfeld, Janice Averilla, Sumedha Gunewardena, Steven A. Weinman, Irina Tikhanovich – 24 April 2022 – Alcohol‐associated liver disease is a major cause of alcohol‐related mortality. However, the mechanisms underlying disease progression are not fully understood. Recently we found that liver molecular pathways are altered by alcohol consumption differently in males and females. We were able to associate these sex‐specific pathways with two upstream regulators: H3K4‐specific demethylase enzymes KDM5B and KDM5C.

Disha Sharma, Gil Ben Yakov, Devika Kapuria, Gracia Viana Rodriguez, Meital Gewirtz, James Haddad, David E. Kleiner, Christopher Koh, Jenna R. E. Bergerson, Alexandra F. Freeman, Theo Heller – 24 April 2022 – Inborn errors of immunity (IEIs) consist of numerous rare, inherited defects of the immune system that affect about 500,000 people in the United States. As advancements in diagnosis through genetic testing and treatment with targeted immunotherapy and bone marrow transplant emerge, increasing numbers of patients survive into adulthood posing fresh clinical challenges.

Aparna Goel, Allison Kwong – 23 April 2022

Aparna Goel, Allison Kwong – 23 April 2022