M A Ramsay, B R Simpson, A T Nguyen, K J Ramsay, C East, G B Klintmalm – 30 December 2003 – Advanced liver disease with portal hypertension may be associated with pulmonary hypertension. A review of 1,205 consecutive liver transplant patients was made to assess the incidence and severity of pulmonary hypertension in patients with end‐stage liver disease. Postoperative data were reviewed to determine if outcome was influenced and, in patients with severe pulmonary hypertension, whether pulmonary hypertension was reversed after transplantation.

D J Plevak, L C Torsher – 30 December 2003

N L Ascher – 30 December 2003

M Benjamin – 30 December 2003

G Everson, G Bharadhwaj, R House, M Talamantes, B Bilir, R Shrestha, I Kam, M Wachs, F Karrer, B Fey, C Ray, T Steinberg, C Morgan, T P Beresford – 30 December 2003

30 December 2003

Adriano Reuben – 30 December 2003

30 December 2003

Paolo Angeli, Roberta Volpin, Giorgio Gerunda, Raffaella Craighero, Paola Roner, Roberto Merenda, Piero Amodio, Antonietta Sticca, Lorenza Caregaro, Alvise Maffei‐Faccioli, Angelo Gatta – 30 December 2003 – The aim of the study was to verify the effects of the administration of an inhibitor of the release of endogenous vasodilators together with a vasoconstrictor agent in patients with hepatorenal syndrome (HRS). This new medical perspective was compared with a traditional medical approach for HRS, such as the infusion of nonpressor doses of dopamine to produce renal vasodilation.

Satoshi Mochida, Masahiro Arai, Akihiko Ohno, Fumio Yamanobe, Keiko Ishikawa, Atsushi Matsui, Ikuo Maruyama, Hisao Kato, Kenji Fujiwara – 30 December 2003 – Activated Kupffer cells provoke massive liver necrosis after endotoxin stimulation through microcirculatory disturbance caused by sinusoidal fibrin deposition in rats undergoing 70% hepatectomy. In these rats, serum activities of purine nucleoside phosphorylase (PNP) and alanine transaminase (ALT) were increased at 1 and 5 hours, respectively, following endotoxin administration.