Genome‐wide meta‐analysis identifies susceptibility loci for autoimmune hepatitis type 1

You Li, Ying Sun, Yanmin Liu, Bangmao Wang, Jia Li, Hanxiao Wang, Haiping Zhang, Xiaoyi Wang, Xu Han, Qiuxiang Lin, Yang Zhou, Lilin Hu, Yuhu Song, Jie Bao, Ling Gong, Mengying Sun, Xiaoling Yuan, Xinhe Zhang, Min Lian, Xiao Xiao, Qi Miao, Qixia Wang, Ke‐Ke Li, Shiyu Du, Anlin Ma, Yiling Li, Jie Xu, Shanhong Tang, Junping Shi, Yun Xu, Ling Yang, Jiming Zhang, Zuxiong Huang, Lu Zhou, Yong Cui, Michael F. Seldin, M. Eric Gershwin, Huiping Yan, Zhengsheng Zou, Xianbo Zuo, Ruqi Tang, Xiong Ma, the Chinese AIH Consortium – 18 February 2022

Immunoglobulin M: A Neglected Serum Biomarker in Treatment‐Naive Primary Biliary Cholangitis With Normal Alkaline Phosphatase

Dawei Ding, Guoyun Xuan, Yinan Hu, Jiahao Yu, Yansheng Liu, Guanya Guo, Shuoyi Ma, Fangfang Yang, Siyuan Tian, Gang Ma, Ling Chen, Xinmin Zhou, Yulong Shang, Ying Han – 18 February 2022 – The diagnosis of primary biliary cholangitis (PBC) in patients with seropositive anti‐mitochondrial antibody (AMA) but normal alkaline phosphatase (ALP) depends on a liver biopsy. We aimed to reveal potential serum biomarkers that could suggest the necessity of a liver biopsy in such patients. Retrospective analysis was performed.

Long‐term outcomes of crossmatch positive simultaneous liver–kidney transplantations in the United States

Samy Riad, Elizabeth S. Aby, Phuoc Le Nguyen, Scott Jackson, Nicholas Lim, John Lake – 17 February 2022 – The long‐term outcomes of positive crossmatch (+XM) simultaneous liver–kidney (SLK) transplantations are conflicting. We examined the association between crossmatch status and SLK outcomes in recipients discharged on tacrolimus and mycophenolate with or without steroids. We analyzed the Scientific Registry of Transplant Recipients for all primary SLK recipients between 2003 and 2020 with available crossmatch and induction data.

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