Autoimmune hepatitis in pregnancy: Pearls and pitfalls

Y. Y. Chung, Michael A. Heneghan – 18 February 2022 – Autoimmune hepatitis (AIH) in pregnancy has many unique considerations. Evidence provided from single center studies with patient level data and nationwide population studies provide valuable insight into this complex situation. Because a planned pregnancy is a safer pregnancy, preconception counseling is a crucial opportunity to optimize care and risk stratify women with AIH.

Autoimmune hepatitis in pregnancy: Pearls and pitfalls

Y. Y. Chung, Michael A. Heneghan – 18 February 2022 – Autoimmune hepatitis (AIH) in pregnancy has many unique considerations. Evidence provided from single center studies with patient level data and nationwide population studies provide valuable insight into this complex situation. Because a planned pregnancy is a safer pregnancy, preconception counseling is a crucial opportunity to optimize care and risk stratify women with AIH.

Albumin Lipidomics Reveals Meaningful Compositional Changes in Advanced Cirrhosis and Its Potential to Promote Inflammation Resolution

Mireia Casulleras, Roger Flores‐Costa, Marta Duran‐Güell, Ingrid W. Zhang, Cristina López‐Vicario, Anna Curto, Javier Fernández, Vicente Arroyo, Joan Clària – 17 February 2022 – Albumin infusions are therapeutically used to revert hypoalbuminemia and to replace the extensively oxidized albumin molecule circulating in patients with acutely decompensated (AD) cirrhosis. Because albumin has high affinity for lipids, here we characterized the albumin lipidome in patients with AD and explored the albumin effects on the release of fatty acid (FA)–derived lipid mediators by peripheral leukocytes.

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