Sexual transmission of hepatitis D virus infection in Taiwan

Jaw‐Ching Wu, Shou‐Dong Lee, Sugantha Govindarajan, Hwa‐Chen Lin, Pesus Chou, Yan‐Jenn Wang, Shoou‐Yih Lee, Yang‐Te Tsai, Kwang‐Juei Lo, Ling‐Pai Ting – 1 June 1990 – Multivariate analysis of the risk factors for hepatitis D virus infection among 53 men with acute hepatitis D virus superinfection, 59 men with acute exacerbation of chronic hepatitis B and 54 asymptomatic male hepatitis B carriers revealed that sexual contact with prostitutes and use of nondisposable needles were the factors significantly associated with hepatitis D virus infection in Taiwan (odds ratio = 5.5, 95% confidence

Hepatitis B virus and hepatitis D virus replication in HBsAg‐positive fulminant hepatitis

Antoni Mas, María Buti, Rafael Esteban, José M. Sánchez‐Tapias, Josep Costa, Rosendo Jardí, Miquel Bruguera, Jaime Guardia, Joan Rodés – 1 June 1990 – Hepatitis B virus DNA and hepatitis D virus RNA, the most sensitive markers of hepatitis B and hepatitis D virus replication, were sought by molecular hybridization with radioactive probes in serial serum samples from 29 consecutive patients with HBsAg‐positive fulminant hepatitis. Nineteen patients had evidence of hepatitis D virus infection, as assessed by the presence in serum of delta antigen, anti‐delta antibodies, or both.

Radiologic ablation of the gallbladder: An alternative to cholecystectomy in the twenty‐first century

E. C. Martin – 1 June 1990 – Twenty pigs underwent (a) cystic duct occlusion by means of fluoroscopically guided transcatheter endoluminal bipolar radio‐frequency (RF) electrocoagulation and (b) gallbladder sclerotherapy with one of two different regimens of ethanol and sodium tetradecylsulfate (STS). Serum ethanol levels and hepatic enzyme tests showed no acute toxicity. Postmortem histologic studies showed that the bile ducts beyond the occlusion site remained entirely unaffected in all animals.

Glucuronidation of oxazepam is not spared in patients with hepatic encephalopathy

Jesper Sonne, Per Buch Andreasen, Steffen Loft, Martin Døsing, Frederik Andreasen – 1 June 1990 – The disposition of oral oxazepam was investigated in seven patients with decompensated cirrhosis and encephalopathy and in nine healthy individuals to further examine the hypothesis of preservation of glucuronidation in liver disease. The patients showed a severe reduction in the quantitative liver function as assessed by estimation of the clearance of antipyrine; the median value was 9 ml. min−1 and the range was 6 to 12 ml. min−1.

Interaction between hepatitis B surface proteins and monomeric human serum albumin

Bernd Krone, Angela Lenz, Klaus‐Hinrich Heermann, Maria Seifer, Lu Xuangyong, Wolfram H. Gerlich – 1 June 1990 – HBsAg is known to bind to human serum albumin polymerized by glutaraldehyde, human serum albumin has been found in preparations of HBsAg by several investigators. However, it is not yet known whether natural human serum albumin binds to hepatitis B virus under physiological conditions. We studied the binding between natural or recombinant HBsAg and monomeric human serum albumin by immunological, biochemical and biophysical methods.

Hormonal responses to large paracentesis: Are discordant results due to technologic differences?

Joan Rodes – 1 June 1990 – The use of paracentesis has recently been reproposed as a safe and effective alternative to diuretics for management of ascites. We have investigated the clinical and biochemical effects of large‐volume paracentesis in 19 cirrhotics with tense ascites, and the relative changes in the hormones involved in sodium and water renal handling. Plasma renin activity (PRA), aldosterone (PA), and arginine vasopressin (AVP) levels and conventional liver and renal function tests were measured before and 1, 2 and 7 days after the paracentesis.

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