pH regulation in human gallbladder bile: Study in patients with and without gallstones
Chantal Marteau, Bernard Sastre, Nicola Iconomidis, Henri Portugal, Anne‐Marie Pauli, André Gérolami – 1 June 1990 – Samples of gallbladder bile obtained from 25 controls and 34 patients with pigment (28 cases) or cholesterol (6 cases) gallstones were studied to establish whether disturbances in regulation of the biliary pH are likely to play a role in the pathogenesis of gallstones. Samples were assayed for pH, Pco2 and concentrations of sodium, bicarbonate and calcium (total and ionized). Saturation of bile in calcium carbonate was calculated.