Hepatic carbonic anhydrase inhibition by diuretic drugs
Thomas H. Maren – 1 September 1987 – 1. In isolated perfused rat liver, urea synthesis is rapid and reversibly inhibited not only by the well‐known carbonic anhydrase inhibitors acetazolamide, methazolamide and ethoxzolamide, but also by diuretics, like xipamide, mefruside, chlortalidone, and chlorothiazide. Furosemide was without effect.