Donald M. Small – 1 September 1987 – Although bile acid and bile lipid metabolism have been studied in established cholelithiasis, little is known about them in patients destined to develop gall stones, but in whom the stones have not yet appeared (prestone gall stone disease). After confirmed complete gall stone dissolution and withdrawal of treatment, gall stones recur frequently.
Rafael E. Cuellar, Ralph Tarter, Amy Hays, David H. Van Thiel – 1 September 1987 – A case of a 20‐yr‐old female with possible “alcoholic hepatitis” and a mixed micro/macronodular cirrhosis occurring in association with overt bulimia and a history of anorexia nervosa, but without any objective evidence of either alcoholism or alcohol abuse, is reported. The possible factors that may have contributed, either alone or in combination, to produce this unusual occurrence are discussed.
Flavio Moroni, Oliviero Riggio, Vincenzo Carlà, Vittorio Festuccia, Florio Ghinelli, Ignazio R. Marino, Manuela Merli, Laura Natali, Giovanni Pedretti, Franco Fiaccadori, Livio Capocaccia – 1 September 1987 – The aim of the study was to verify the role of γ‐aminobutyric acid in the pathogenesis of hepatic encephalopathy occurring in cirrhotic patients by attempting to correlate plasma and cerebrospinal fluid content of authentic γ‐aminobutyric acid with the neurological manifestations of hepatic encephalopathy.
Kunio Okuda – 1 September 1987 – A total of 105 cases of fulminant hepatitis sen during the period fom January 1979 to December 1983 and filed by the pediatric services of major hospitals throughout Japan with the diagnostic criteria set by the 12th Inuyama Liver Symposium were analyzed. The male:Female atio was 2:1. Fifty‐six per cent of he cases werre younge than 2 years and 29.5% were thought to be due to hepaitis B infection. The majority of B‐type fulminant heptitis cases younger than 6 months not related to blood transfusion had been born to HBeAg‐negative caie mohers.
Harold O. Conn, Abby Van Voorhees, Sidney N. Klaus – 1 September 1987 – Although paraneoplastic phenomena occur frequently in patients with hepatocellular carcinoma, cutaneous changes have rarely been reported. During the past two years, ten South African blacks with hepatocellular carcinoma and pityriasis rotunda have been seen in a single hospital. The rash affected the trunk, especially the lower back and buttocks. The lesions ranged in size from 1.5 to 25 cm and were always multiple.
Dale C. Snover – 1 September 1987 – The histologic findings in the original liver obtained from 9 liver allograft patients with active B virus hepatitis were compared with 28 post‐transplant pathology specimens. All specimens were studied with the use of light and immunohistochemical microscopy in conjunction with pertinent clinical data. Eight of the 9 patients had chronic active hepatitis B (HB) with cirrhosis, prior to transplant, one of which had coexistent hepatocellular carcinoma. The ninth patient had fulminant hepatic necrosis secondary to acute HB prior to transplantation.
Scott M. Grundy, Sarah C. Kalser – 1 September 1987
David J. Schneiderman, David M. Arenson, John P. Cello, William Margaretten, Thomas E. Weber – 1 September 1987 – The spectrum of liver disease in patients with acquired immune deficiency syndrome (AIDS) and the clinical impact of diagnostic percutaneous liver biopsy in this population were evaluated by a retrospective review of hepatic histology, clinical features and laboratory data in 85 patients (26 biopsies, 59 autopsies). Only 1 (3.8%) biopsy and 9 (15%) postmortem livers were histologically normal.
Peter F. Malet, Y. Peled – 1 September 1987
Joseph Alcorn, Mario Chojkier – 1 September 1987 – Immunolocalization of type III collagen and procollagen in cirrhotic human liver was studied using monoclonal antibody specific for the helical determinant of type III collagen extracted from human placenta. Deparaffinized, trypsin‐treated cirrhotic liver sections from 8 autopsy cases were examined by the unlabeled peroxidase‐antiperoxidase and immunofluorescence techniques.