Marcello Piazza, Guglielmo Borgia, Jane Crowell, Salvatore Nappa, Alberto Lambiase, Daniel Perrissoud, Werner Schreil – 1 September 1985 – We report a morphometric study on the effect of 3‐palmitoyl‐(+)‐catechin on phagocytic activity of latex particles by Kupffer cells in guinea pig liver. We found an increase in the density of latex particles in Kupffer cells of animals treated with 3‐palmitoyl‐(+)‐catechin. The volume and density of Kupffer cells of treated animals increased (p < 0.01); there was no significant difference in surface density of the plasma membrane.

D. Montgomery Bissell – 1 September 1985

1 September 1985

Barry J. Potter, Roger W. G. Chapman, Rosa M. Nunes, Dario Sorrentino, Sheila Sherlock – 1 September 1985 – The metabolism of transferrin was studied using purified 125I‐labeled transferrin in 11 alcoholic patients; six with fatty liver and five with cirrhosis. Six healthy subjects whose alcohol intake was les than 40 gm daily were studied as a control group.

Francis V. Chisari, Mary Nakamura, David R. Milich, Keith Han, Daniel Molden, Geert G. Leroux‐Roels – 1 September 1985 – By manipulating dietary sugar intake and perfusate glucose concentration, we have identified two independent hepatic immunoregulatory molecules produced by the perfused rat liver. The first is released by injured hepatocytes, appears in perfusates together with hepatocellular glutamic pyruvic transaminase, is quantitatively inhibited by exogenous L‐arginine and coelutes with arginase on high‐pressure liquid chromatography.

Teruo Mori, Yoshio Mori, Hiromichi Yoshida, Shiro Ueda, Makoto Ogawa, Kenji Iesato, Yoko Wakashin, Masafumi Wakashin, Kunio Okuda – 1 September 1985 – Spleen cells obtained from C57BL/6 (B6) mice with an experimental autoimmune hepatitis were transferred to normal C57BL/6 recipient mice. Most prominent liver damages occurred in the recipient mice injected with sensitized nylon wool column‐adherent spleen cells from the donor mice.

Yacov R. Stollman, Lorenz Theilmann, Richard J. Stockert, Allan W. Wolkoff – 1 September 1985 – In previous studies, we found that uptake of bilirubin and asialoorosomucoid is depressed in regenerating rat liver. To determine what role the hepatic cytoskeleton plays in this modulation of uptake, animals were treated with colchicine, an inhibitor of microtubular polymerization. Normal unoperated rats or rats following two‐thirds hepatectomy or sham surgery were injected with colchicine, lumicolchicine (50 μg per 100 gm of body weight, i.p.) or normal saline.

David H. Van Thiel, Mahendra Udani, Robert R. Schade, Agit Sanghvi, Thomas E. Starzl – 1 September 1985 – The thyroid hormones T4, T3, rT3 and TSH were assayed in 134 adult patients evaluated and accepted as potential liver transplant candidates at the Universty of Pittsburgh from March, 1981 to December, 1983. The subsequent course of these patients was evaluated with respect to the levels of these hormones obtained at the time of acceptance for transplantation.

Thomas L. Sell, Bruce A. Runyon, John C. Hoefs – 1 September 1985

Fumio Imazeki, Masao Omata, Osamu Yokosuka, Yasuhisa Matsuyama, Yoshimi Ito, Kunio Okuda – 1 September 1985 – An assay for DNA polymerase reaction products using slab gel electrophoresis and autoradiography was compared with the spot hybridization technique for the detection of hepatitis B virus DNA in 317 blood samples. The former could identify the nature and size of DNA on electrophoresis, and reduce potentially false‐positive results due to artifacts.