Neighborhood poverty is associated with failure to be waitlisted and death during liver transplantation evaluation

Kawthar A. Mohamed, Marwan Ghabril, Archita Desai, Eric Orman, Kavish R. Patidar, John Holden, Susan Rawl, Naga Chalasani, Chandra Shekhar Kubal, Lauren Nephew – 6 April 2022 – Liver transplantation (LT) is the final step in a complex care cascade. Little is known about how race, gender, rural versus urban residence, or neighborhood socioeconomic indicators impact a patient's likelihood of LT waitlisting or risk of death during LT evaluation. We performed a retrospective cohort study of adults referred for LT to the Indiana University Academic Medical Center from 2011 to 2018.

Severe acute respiratory syndrome coronavirus 2 antibody response to a third dose of homologous messenger RNA vaccination in liver transplantation recipients

Alexandra T. Strauss, Amy Chang, Jennifer L. Alejo, Teresa P.‐Y. Chiang, Nicole F. Hernandez, Laura B. Zeiser, Brian J. Boyarsky, Robin K. Avery, Aaron A. R. Tobian, Macey L. Levan, Daniel S. Warren, Allan B. Massie, Jacqueline M. Garonzik‐Wang, Dorry L. Segev, William A. Werbel – 6 April 2022

Fecal microbiota transplant improves cognition in hepatic encephalopathy and its effect varies by donor and recipient

Patricia P. Bloom, John Donlan, Mariam Torres Soto, Michael Daidone, Elizabeth Hohmann, Raymond T. Chung – 4 April 2022 – Early data suggest fecal microbiota transplant (FMT) may treat hepatic encephalopathy (HE). Optimal FMT donor and recipient characteristics are unknown. We assessed the safety and efficacy of FMT in patients with prior overt HE, comparing five FMT donors. We performed an open‐label study of FMT capsules, administered 5 times over 3 weeks. Primary outcomes were change in psychometric HE score (PHES) and serious adverse events (SAEs).

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