Distinct Hepatic Gene‐Expression Patterns of NAFLD in Patients With Obesity

Sonu Subudhi, Hannah K. Drescher, Laura E. Dichtel, Lea M. Bartsch, Raymond T. Chung, Matthew M. Hutter, Denise W. Gee, Ozanan R. Meireles, Elan R. Witkowski, Louis Gelrud, Ricard Masia, Stephanie A. Osganian, Jenna L. Gustafson, Steve Rwema, Miriam A. Bredella, Sangeeta N. Bhatia, Andrew Warren, Karen K. Miller, Georg M. Lauer, Kathleen E. Corey – 10 August 2021 – Approaches to manage nonalcoholic fatty liver disease (NAFLD) are limited by an incomplete understanding of disease pathogenesis.

Anticancer Effect of Statins in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma

Hae Lim Lee, Sung Won Lee, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Ho Joong Choi, Gun Hyung Na, Young Kyoung You, Il Young Park, Dong Goo Kim – 8 August 2021 – The anticancer effect of statins is drawing attention. However, it is unclear whether statin use reduces the risk of hepatocellular carcinoma (HCC) recurrence in patients who undergo liver transplantation (LT) for HCC. Consecutive patients who underwent LT for HCC between 1995 and 2019 were enrolled.

Liver Transplantation for Acute Liver Injury in Asians Is More Likely Due to Herbal and Dietary Supplements

Varun Kesar, Lindsey Channen, Umair Masood, Priya Grewal, Jawad Ahmad, Nitzan C. Roth, Joseph A. Odin – 8 August 2021 – Drug‐induced liver injury (DILI) due to medications and herbal and dietary supplements (HDSs) is a major cause of acute liver injury leading to liver transplantation (LT). This study used United Network for Organ Sharing LT data to analyze severe HDS‐induced acute liver injury in the United States.

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