Next Generation Sequencing‐Based Identification of T‐Cell Receptors for Immunotherapy Against Hepatocellular Carcinoma

Yipeng Ma, Jiayu Ou, Tong Lin, Lei Chen, Junhui Chen, Mingjun Wang – 27 February 2021 – Hepatitis B virus (HBV)‐related hepatocellular carcinoma (HCC) remains a global health concern, and HBV proteins may be ideal targets for T cell‐based immunotherapy for HCC. There is a need for fast and efficient identification of HBV‐specific T cell receptors (TCRs) for the development of TCR‐transduced T (TCR‐T) cell‐based immunotherapy.

Renal Outcomes After Simultaneous Liver‐Kidney Transplantation: Results from the US Multicenter Simultaneous Liver‐Kidney Transplantation Consortium

Pratima Sharma, Zhiyu Sui, Min Zhang, John C. Magee, Pranab Barman, Yuval Patel, Aaron Schluger, Kara Walter, Scott W. Biggins, Giuseppe Cullaro, Randi Wong, Jennifer C. Lai, Jennifer Jo, Jasmine Sinha, Lisa VanWagner, Elizabeth C. Verna – 27 February 2021 – Simultaneous liver‐kidney transplantation (SLKT) is increasingly common in the United States. However, little is known about the renal‐related outcomes following SLKT, which are essential to maximize the health of these allografts. We examined the factors impacting renal function following SLKT.

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