Complex Liver Transplantation Using Venovenous Bypass With an Atypical Placement of the Portal Vein Cannula

Giuseppe Rocco, Antonio Siniscalchi, Matteo Serenari, Guido Fallani, Giuliana Germinario, Lorenzo Maroni, Enrico Prosperi, Massimo Del Gaudio, Federica Odaldi, Matteo Cescon, Matteo Ravaioli – 28 August 2020 – In liver transplantation (LT) medical literature, venovenous bypass (VVB) with the interposition of a venous graft attached to the inferior mesenteric vein (IMV) or to the splenic vein (SV) has not been reported previously. Here, we report the decompression of the portomesenteric compartment in 2 patients with complex cases of orthotopic LT.

Fatigue and Pruritus in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: The Impact on Patient‐Reported Outcomes

Zobair M Younossi, Vincent Wai‐Sun Wong, Quentin M. Anstee, Manuel Romero‐Gomez, Michael H. Trauner, Stephen A. Harrison, Eric J. Lawitz, Takeshi Okanoue, Marianne Camargo, Kathryn Kersey, Robert P. Myers, Zachary Goodman, Maria Stepanova – 28 August 2020 – Fatigue and pruritus are common in patients with chronic liver diseases of all etiologies, but clinical awareness is mostly restricted to those with cholestatic liver diseases. We assessed the impact of fatigue and pruritus on patient‐reported outcomes (PROs) of patients with advanced nonalcoholic steatohepatitis (NASH).

Genome‐wide Association Study and Meta‐analysis on Alcohol‐Associated Liver Cirrhosis Identifies Genetic Risk Factors

Tae‐Hwi Schwantes‐An, Rebecca Darlay, Philippe Mathurin, Steven Masson, Suthat Liangpunsakul, Sebastian Mueller, Guruprasad P. Aithal, Florian Eyer, Dermot Gleeson, Andrew Thompson, Beat Muellhaupt, Felix Stickel, Michael Soyka, David Goldman, Tiebing Liang, Lawrence Lumeng, Munir Pirmohamed, Bertrand Nalpas, Jean‐Marc Jacquet, Romain Moirand, Pierre Nahon, Sylvie Naveau, Pascal Perney, Greg Botwin, Paul S. Haber, Helmut K. Seitz, Christopher P. Day, Tatiana M. Foroud, Ann K. Daly, Heather J. Cordell, John B. Whitfield, Timothy R.

Technical Choices in Pediatric Living Donor Liver Transplantation: The Path to Reduce Vascular Complications and Improve Survival

João Seda Neto, Eduardo A. Fonseca, Rodrigo Vincenzi, Renata Pugliese, Marcel R. Benavides, Karina Roda, Gilda Porta, Irene K. Miura, Adriana Porta, Christian Borges, Vera Baggio, Flavia H. Feier, Hsiang Teng, Mônica L. Rodrigues, Fernanda C. Iwase, Mário Kondo, Paulo Chapchap – 27 August 2020 – Pediatric living donor liver transplantation (PLDLT) is a successful therapeutic option for children with chronic and acute liver disease. After early transplant results, many technical advancements were introduced in the field to reduce the rate of complications and improve survival.

Antibody Response to Severe Acute Respiratory Syndrome‐ Corona Virus 2, Diagnostic and Therapeutic Implications

Yuval Ishay, Asa Kessler, Asaf Schwarts, Yaron Ilan – 26 August 2020 – The immune response against severe acute respiratory syndrome‐corona virus 2 (SARS‐CoV‐2) is comprised of both cellular and humoral arms. While current diagnostic methods are mainly based on polymerase chain reaction, they suffer from insensitivity. Therefore, antibody‐based serologic tests are being developed to achieve higher sensitivity and specificity.

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