Genome‐Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study

S. Lani Park, Yuqing Li, Xin Sheng, Victor Hom, Lucy Xia, Kechen Zhao, Loreall Pooler, V. Wendy Setiawan, Unhee Lim, Kristine R. Monroe, Lynne R. Wilkens, Bruce S. Kristal, Johanna W. Lampe, Meredith Hullar, John Shepherd, Lenora L. M. Loo, Thomas Ernst, Adrian A. Franke, Maarit Tiirikainen, Christopher A. Haiman, Daniel O. Stram, Loïc Le Marchand, Iona Cheng – 25 June 2020 – The global rise in fatty liver is a major public health problem. Thus, it is critical to identify both global and population‐specific genetic variants associated with liver fat.

Immunosuppression in Donation After Circulatory Death Liver Transplantation: Can Induction Modify Graft Survival?

Kevin Ig‐Izevbekhai, David S. Goldberg, Seth J. Karp, David P. Foley, Peter L. Abt – 24 June 2020 – Recipients of donation after circulatory death (DCD) LTs historically have an increased risk of graft failure. Antibody induction (AI) with antithymocyte globulin (ATG) or anti‐interleukin 2 receptor (anti‐IL2R) immunotherapy may decrease the incidence of graft failure by mitigating ischemia/reperfusion injury.

Comparison of Clinical Outcomes of Induction Regimens in Patients Undergoing Liver Transplantation for Acute Liver Failure

Chimaobi M. Anugwom, Justin R. Parekh, Christine Hwang, Malcolm MacConmara, William M. Lee, Thomas M. Leventhal – 24 June 2020 – Spontaneous survival rates in acute liver failure (ALF) are vastly improved by liver transplantation (LT). However, the value of induction agents beyond steroids continues to be debated. To understand the potential benefit of different induction regimens in the ALF population, we compared overall survival of recipients undergoing LT in the United States for ALF.

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