Coronavirus Disease 2019 Infection Requires Strengthening of the Chronic Care Model: The Impact on Liver Transplant Practice at a High‐Volume Center in Italy

Paolo De Simone, Fabio Melandro, Emanuele Balzano, Giovanni Tincani, Gabriele Catalano, Davide Ghinolfi, Juri Ducci, Paola Carrai, Stefania Petruccelli, Giandomenico Biancofiore – 15 June 2020

Association of Perfusion Characteristics and Posttransplant Liver Function in Ischemia‐Free Liver Transplantation

Zhiheng Zhang, Yunhua Tang, Qiang Zhao, Linhe Wang, Caihui Zhu, Weiqiang Ju, Dongping Wang, Lu Yang, Linwei Wu, Maogen Chen, Shanzhou Huang, Ningxin Gao, Zebin Zhu, Yixi Zhang, Chengjun Sun, Wei Xiong, Yuekun Shen, Yi Ma, Anbin Hu, Xiaofeng Zhu, Jian Rong, Changjie Cai, Zhiyong Guo, Xiaoshun He – 15 June 2020 – It has been shown that normothermic machine perfusion (NMP), a novel preservation method, is able to assess and resuscitate liver grafts with risk factors. However, there is no consistent criteria for the assessment of liver grafts with NMP.

Liver Transplantation From Controlled Donors After Circulatory Death Using Normothermic Regional Perfusion: An Initial French Experience

Corinne Antoine, Carine Jasseron, Federica Dondero, Eric Savier, the French National Steering Committee of Donors After Circulatory Death – 12 June 2020 – A national program of controlled donation after circulatory death (cDCD) began in France in 2014 involving the use of a standardized national protocol that involves the systematic use of normothermic regional perfusion (NRP). In this article, we describe in detail the French cDCD program. Between January 1, 2015, and December 31, 2018, 225 livers were offered for donation, resulting in 123 cDCD liver transplantations (LTs).

Microbiomics, Metabolomics, Predicted Metagenomics, and Hepatic Steatosis in a Population‐Based Study of 1,355 Adults

Louise J.M. Alferink, Djawad Radjabzadeh, Nicole S. Erler, Dina Vojinovic, Carolina Medina‐Gomez, André G. Uitterlinden, Robert J. Knegt, Najaf Amin, M. Arfan Ikram, Harry L.A. Janssen, Jessica C. Kiefte‐de Jong, Herold J. Metselaar, Cornelia M. Duijn, Robert Kraaij, Sarwa Darwish Murad – 12 June 2020

Donation After Circulatory Death Is Associated With Similar Posttransplant Survival in All but the Highest‐Risk Hepatocellular Carcinoma Patients

Jordyn Silverstein, Garrett Roll, Jennifer L. Dodge, Joshua D. Grab, Francis Y. Yao, Neil Mehta – 12 June 2020 – Liver transplantation (LT) recipients with hepatocellular carcinoma (HCC) receive a higher proportion of livers from donation after circulatory death (DCD) donors compared with non‐HCC etiologies. Nevertheless, data on outcomes in patients with HCC receiving DCD grafts are limited. We evaluated the influence of DCD livers on post‐LT outcome among HCC patients.

Machine Perfusions in Liver Transplantation: The Evidence‐Based Position Paper of the Italian Society of Organ and Tissue Transplantation

Davide Ghinolfi, Quirino Lai, Daniele Dondossola, Riccardo De Carlis, Marinella Zanierato, Damiano Patrono, Stefano Baroni, Domenico Bassi, Fabio Ferla, Andrea Lauterio, Chiara Lazzeri, Paolo Magistri, Fabio Melandro, Duilio Pagano, Daniele Pezzati, Matteo Ravaioli, Erion Rreka, Luca Toti, Alberto Zanella, Patrizia Burra, Salvatore Petta, Massimo Rossi, Philippe Dutkowski, Wayel Jassem, Paolo Muiesan, Cristiano Quintini, Markus Selzner, Umberto Cillo – 10 June 2020 – The use of machine perfusion (MP) in liver transplantation (LT) is spreading worldwide.

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