Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates

Ani Kardashian, Jin Ge, Charles E. McCulloch, Matthew R. Kappus, Michael A. Dunn, Andres Duarte‐Rojo, Michael L. Volk, Robert S. Rahimi, Elizabeth C. Verna, Daniel R. Ganger, Daniela Ladner, Jennifer L. Dodge, Brian Boyarsky, Mara McAdams‐DeMarco, Dorry L. Segev, Jennifer C. Lai – 3 June 2020

Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway

Xin Wang, Ling‐yue Dong, Qu‐jing Gai, Wei‐lun Ai, Yuan Wu, Wei‐chun Xiao, Jing Zhang, Wei An – 2 June 2020 – It is well known that excessive cholesterol accumulation within hepatocytes deteriorates nonalcoholic fatty liver disease (NAFLD). Augmenter of liver regeneration (ALR) has been reported to alleviate NAFLD through anti‐apoptosis; however, whether ALR could protect liver from cholesterol‐induced NAFLD remains unclear.

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