Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Advanced Liver Disease: An Exploratory Meta‐Analysis

Francesco Violi, Annarita Vestri, Danilo Menichelli, Arianna Di Rocco, Daniele Pastori, Pasquale Pignatelli – 7 May 2020 – Direct oral anticoagulants (DOACs) have had a positive impact in preventing cardioembolic stroke in patients with atrial fibrillation (AF) who were associated with lower bleeding complications; however, data on subjects with concomitant advanced liver diseases (ALDs) are poor. This meta‐analysis evaluates bleeding and thromboembolic complications in patients with coexisting AF and ALD who were treated with DOACs or vitamin K antagonists (VKAs).

Liver Transplant Survivorship

Jennifer C. Lai, Nneka N. Ufere, John C. Bucuvalas – 6 May 2020 – For both children and adults with end‐stage liver disease, liver transplantation represents a lifelong treatment, not a cure. The physical and psychological process of undergoing transplantation begins well before the surgery itself. Concerns regarding suffering and death from end‐stage liver disease are replaced by a lifelong need for multiple medications, ongoing monitoring of graft function, and heightened vigilance for complications related not only to the transplant itself but to longterm immunosuppression.

Subscribe to