Major Histocompatibility Complex Class I‐Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease

Azza Karrar, Bijal Rajput, Siddharth Hariharan, Dinan Abdelatif, Mohamad Houry, Ali Moosvi, Irfan Ali, Daisong Tan, Sohailla Noor, Donna Esmaeili, Sean Felix, Lakshmi Alaparthi, Munkhzul Otgonsuren, Brian Lam, Zachary D. Goodman, Zobair M. Younossi – 30 September 2020 – Major histocompatibility complex class I‐related chain A (MICA) is a highly polymorphic gene that modulates immune surveillance by binding to its receptor on natural killer cells, and its genetic polymorphisms have been associated with chronic immune‐mediated diseases.

Early Predictors of Short‐Term Prognosis in Acute and Acute Severe Autoimmune Hepatitis

Maaike Biewenga, Akin Inderson, Maarten E. Tushuizen, A. Stijn L.P. Crobach, Bart Hoek – 30 September 2020 – Presentation of autoimmune hepatitis (AIH) can differ from nonacute to acute autoimmune hepatitis (A‐AIH) with jaundice and acute severe autoimmune hepatitis (AS‐AIH) with jaundice and coagulopathy. The aim of the study was to evaluate the short‐term prognosis of different presentations of AIH and the influence of liver function improvement on short‐term prognosis.

The Impact of COVID‐19 on Organ Donation, Procurement, and Liver Transplantation in the United States

Jonathan Merola, Michael L. Schilsky, David C. Mulligan – 29 September 2020 – The coronavirus disease 2019 pandemic has had an impact on all facets of our health care system, including life‐saving procedures like organ transplantation. Concerns for potential exposure to the causative severe acute respiratory syndrome coronavirus type 2 have profoundly altered the process of organ donation and recovery that is vital to the execution of organ transplantation.

The Impact of COVID‐19 on Organ Donation, Procurement, and Liver Transplantation in the United States

Jonathan Merola, Michael L. Schilsky, David C. Mulligan – 29 September 2020 – The coronavirus disease 2019 pandemic has had an impact on all facets of our health care system, including life‐saving procedures like organ transplantation. Concerns for potential exposure to the causative severe acute respiratory syndrome coronavirus type 2 have profoundly altered the process of organ donation and recovery that is vital to the execution of organ transplantation.

Reducing the Global Burden of Alcohol‐Associated Liver Disease: A Blueprint for Action

Sumeet K. Asrani, Jessica Mellinger, Juan P. Arab, Vijay H. Shah – 28 September 2020 – Alcohol‐associated liver disease (ALD) is a major driver of global liver related morbidity and mortality. There are 2.4 billion drinkers (950 million heavy drinkers) and the lifetime prevalence of any alcohol use disorder (AUD) is 5.1%‐8.6%. In 2017, global prevalence of alcohol‐associated compensated and decompensated cirrhosis was 23.6 million and 2.5 million, respectively.

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