Epidemiology of Hepatocellular Carcinoma

Katherine A. McGlynn, Jessica L. Petrick, Hashem B. El‐Serag – 22 April 2020 – Liver cancer is a major contributor to the worldwide cancer burden. Incidence rates of this disease have increased in many countries in recent decades. As the principal histologic type of liver cancer, hepatocellular carcinoma (HCC) accounts for the great majority of liver cancer diagnoses and deaths. Hepatitis B virus (HBV) and hepatitis C virus (HCV) remain, at present, the most important global risk factors for HCC, but their importance will likely decline in the coming years.

Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans

Rodrigo M. Florentino, Nicolas A. Fraunhoffer, Kazutoyo Morita, Kazuki Takeishi, Alina Ostrowska, Abhinav Achreja, Olamide Animasahun, Nils Haep, Shohrat Arazov, Nandini Agarwal, Alexandra Collin de l'Hortet, Jorge Guzman‐Lepe, Edgar N. Tafaleng, Amitava Mukherjee, Kris Troy, Swati Banerjee, Shirish Paranjpe, George K. Michalopoulos, Aaron Bell, Deepak Nagrath, Sarah J. Hainer, Ira J.

Outcome for Pediatric Recipients of Macrosteatotic Liver Grafts From Living Donors

Rie Irie, Atsuko Nakazawa, Seisuke Sakamoto, Masahiro Takeda, Yusuke Yanagi, Seiichi Shimizu, Hajime Uchida, Akinari Fukuda, Mureo Kasahara – 20 April 2020 – In deceased donor liver transplantation, a donor liver with moderate (>30%) macrosteatosis used to be considered inappropriate for grafting. We examined the outcomes of children who underwent living donor liver transplantation (LDLT) at the National Center for Child Health and Development whose donor livers had moderate‐to‐severe macrosteatosis.

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