DNA Methylation of Cannabinoid Receptor Interacting Protein 1 Promotes Pathogenesis of Intrahepatic Cholangiocarcinoma Through Suppressing Parkin‐Dependent Pyruvate Kinase M2 Ubiquitination

Diyu Chen, Hao Wu, Xiaode Feng, Yunhao Chen, Zhen Lv, Vishnu Goutham Kota, Junru Chen, Wenxuan Wu, Yuejie Lu, Hua Liu, Yanpeng Zhang, Shusen Zheng, Jian Wu – 21 September 2020

LiverLearning®: 2020 Webinar: Current and Future Disease Burden of HBV: Global and Regional Perspectives

In this on-demand webinar, representative speakers from Africa including North and Sub-Saharan Africa (Mark W. Sonderup, South Africa), East Asia (Jidong Jia, China), West and South Asia (Shiv K. Sarin, India), Europe including Western and Eastern Europe (George V. Papatheodoridis, Greece), North America (Carla Coffin, Canada) and South/Central America (Adrian Gadano) will each talk on HBV disease burden and primary challenges in their respective regions. They will present the current status and predictions for the next decade.

Sequential Use of Normothermic Regional and Ex Situ Machine Perfusion in Donation After Circulatory Death Liver Transplant

Davide Ghinolfi, Daniele Dondossola, Erion Rreka, Caterina Lonati, Daniele Pezzati, Andrea Cacciatoinsilla, Alessia Kersik, Chiara Lazzeri, Alberto Zanella, Adriano Peris, Marco Maggioni, Giandomenico Biancofiore, Paolo Reggiani, Riccardo Morganti, Paolo De Simone, Giorgio Rossi – 18 September 2020 – In Italy, 20 minutes of a continuous flat line on an electrocardiogram are required for declaration of death.

Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute‐on‐Chronic Liver Failure

Shivani Shah, David S. Goldberg, David E. Kaplan, Vinay Sundaram, Tamar H. Taddei, Nadim Mahmud – 18 September 2020 – There is significant interest in identifying risk factors associated with acute‐on‐chronic liver failure (ACLF). In transplant candidates, frailty predicts wait‐list mortality and posttransplant outcomes. However, the impact of frailty on ACLF development and mortality is unknown. This was a retrospective study of US veterans with cirrhosis identified between 2008 and 2016. First hospitalizations were characterized as ACLF or non‐ACLF admissions.

Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis

Mark R. Deneau, Cara Mack, Douglas Mogul, Emily R. Perito, Pamela L. Valentino, Achiya Z. Amir, Matthew DiGuglielmo, Laura G. Draijer, Wael El‐Matary, Katryn N. Furuya, Nitika Gupta, Jessica T. Hochberg, Simon Horslen, M. Kyle Jensen, Maureen M. Jonas, Nanda Kerkar, Bart G.P. Koot, Trevor J. Laborda, Christine K. Lee, Kathleen M. Loomes, Mercedes Martinez, Alexander Miethke, Tamir Miloh, Saeed Mohammad, Nadia Ovchinsky, Girish Rao, Amanda Ricciuto, Pushpa Sathya, Kathleen B. Schwarz, Uzma Shah, Ruchi Singh, Bernadette Vitola, Andréanne Zizzo, Stephen L. Guthery – 18 September 2020

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