Breath Metabolomics Provides an Accurate and Noninvasive Approach for Screening Cirrhosis, Primary, and Secondary Liver Tumors

Galen Miller‐Atkins, Lou‐Anne Acevedo‐Moreno, David Grove, Raed A. Dweik, Adriano R. Tonelli, J. Mark Brown, Daniela S. Allende, Federico Aucejo, Daniel M. Rotroff – 26 April 2020 – Hepatocellular carcinoma (HCC) and secondary liver tumors, such as colorectal cancer liver metastases are significant contributors to the overall burden of cancer‐related morality. Current biomarkers, such as alpha‐fetoprotein (AFP) for HCC, result in too many false negatives, necessitating noninvasive approaches with improved sensitivity.

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Reinout L.P. Roscam Abbing, Folkert Kuipers, Coen C. Paulusma, Henkjan J. Verkade, Albert K. Groen, Ronald P.J. Oude Elferink, Stan F.J. Graaf – 25 April 2020

Functional Comparison of Interferon‐α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon‐α and Interferon‐γ Signaling

Jieliang Chen, Yaming Li, Fritz Lai, Yang Wang, Kathrin Sutter, Ulf Dittmer, Jianyu Ye, Wenjing Zai, Min Liu, Fang Shen, Min Wu, Kongying Hu, Baocun Li, Mengji Lu, Xiaonan Zhang, Jiming Zhang, Jianhua Li, Qingfeng Chen, Zhenghong Yuan – 25 April 2020

A Telephone and Mail Outreach Program Successfully Increases Uptake of Hepatocellular Carcinoma Surveillance

Elizabeth S. Aby, Adam C. Winters, Jonathan Lin, Aileen Bui, Jenna Kawamoto, Matthew B. Goetz, Debika Bhattacharya, Joseph R. Pisegna, Folasade P. May, Arpan A. Patel, Jihane N. Benhammou – 24 April 2020 – Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death worldwide. Society guidelines recommend surveillance with abdominal ultrasound with or without serum alpha‐fetoprotein every 6 months for adults at increased risk of developing HCC. However, adherence is often suboptimal.

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