Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease
Simon Lam, Ruchi Singh, Jonathan R. Dillman, Andrew T. Trout, Suraj D. Serai, Divya Sharma, Rachel Sheridan, Weizhe Su, Lin Fei, Rebekah Karns, Marija M. Haramija, Ged Ridgway, Marc Goldfinger, James E. Squires, Lee A. Denson, Jeffery S. Hyams, Alexander G. Miethke – 24 September 2020 – In autoimmune liver disease (AILD), including autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and overlap syndrome of AIH and PSC (ASC), the presence of biliary injury portends a worse prognosis.