Functional Comparison of Interferon‐α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon‐α and Interferon‐γ Signaling

Jieliang Chen, Yaming Li, Fritz Lai, Yang Wang, Kathrin Sutter, Ulf Dittmer, Jianyu Ye, Wenjing Zai, Min Liu, Fang Shen, Min Wu, Kongying Hu, Baocun Li, Mengji Lu, Xiaonan Zhang, Jiming Zhang, Jianhua Li, Qingfeng Chen, Zhenghong Yuan – 25 April 2020

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Reinout L.P. Roscam Abbing, Folkert Kuipers, Coen C. Paulusma, Henkjan J. Verkade, Albert K. Groen, Ronald P.J. Oude Elferink, Stan F.J. Graaf – 25 April 2020

A Telephone and Mail Outreach Program Successfully Increases Uptake of Hepatocellular Carcinoma Surveillance

Elizabeth S. Aby, Adam C. Winters, Jonathan Lin, Aileen Bui, Jenna Kawamoto, Matthew B. Goetz, Debika Bhattacharya, Joseph R. Pisegna, Folasade P. May, Arpan A. Patel, Jihane N. Benhammou – 24 April 2020 – Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death worldwide. Society guidelines recommend surveillance with abdominal ultrasound with or without serum alpha‐fetoprotein every 6 months for adults at increased risk of developing HCC. However, adherence is often suboptimal.

The L‐α‐Lysophosphatidylinositol/G Protein–Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis

Marcos F. Fondevila, Uxia Fernandez, Maria J. Gonzalez‐Rellan, Natalia Lima, Xabier Buque, Agueda Gonzalez‐Rodriguez, Cristina Alonso, Marta Iruarrizaga‐Lejarreta, Teresa C. Delgado, Marta Varela‐Rey, Ana Senra, Vera Garcia‐Outeiral, Eva Novoa, Cristina Iglesias, Begoña Porteiro, Daniel Beiroa, Cintia Folgueira, Marta Tojo, Jorge L. Torres, Lourdes Hernández‐Cosido, Óscar Blanco, Juan Pablo Arab, Francisco Barrera, Diana Guallar, Miguel Fidalgo, Miguel López, Carlos Dieguez, Miguel Marcos, Maria L. Martinez‐Chantar, Marco Arrese, Carmelo Garcia‐Monzon, Jose M.

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

Stephan Menne, Steffen Wildum, Guido Steiner, Manasa Suresh, Kyle Korolowicz, Maria Balarezo, Changsuek Yon, Marta Murreddu, Xupeng Hong, Bhaskar V. Kallakury, Robin Tucker, Song Yang, John A.T. Young, Hassan Javanbakht – 22 April 2020 – RG7834 is a small‐molecule inhibitor of hepatitis B virus (HBV) gene expression that significantly reduces the levels of hepatitis B surface antigen (HBsAg) and HBV DNA in a humanized liver HBV mouse model.

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