Four Biomarkers Linked to Activation of Cluster of Differentiation 8–Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure

Mike A. Leonis, Alexander G. Miethke, Lin Fei, Sean Maynor, Catherine A. Chapin, Jacob J.H. Bleesing, Estella M. Alonso, Robert H. Squires, for the Pediatric Acute Liver Failure Study Group – 15 April 2020

The Role of Ischemia/Reperfusion Injury in Early Hepatic Allograft Dysfunction

Junbin Zhou, Jian Chen, Qiang Wei, Kourosh Saeb‐Parsy, Xiao Xu – 15 April 2020 – Liver transplantation (LT) is the only available curative treatment for patients with end‐stage liver disease. Early allograft dysfunction (EAD) is a life‐threatening complication of LT and is thought to be mediated in large part through ischemia/reperfusion injury (IRI). However, the underlying mechanisms linking IRI and EAD after LT are poorly understood.

Routine Bile Culture From Liver Donors as Screening of Donor‐Transmitted Infections in Liver Transplantation

Cristina Pérez‐Cameo, Itxarone Bilbao, Mayli Lung, Mireia Caralt, Víctor Vargas, Teresa Pont, Xavier Nuvials, Ibai Los‐Arcos, Lluís Castells, Oscar Len – 14 April 2020 – Bacterial infections are an important threat in the early post–liver transplantation period. Donor‐transmitted infections, although rare, can have high mortality. The utility of routine culture from the donor bile duct as screening of donor‐transmitted infection has not been evaluated. We performed a retrospective study of 200 consecutive liver transplants between 2010 and 2015.

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