A Noncoding Regulatory RNAs Network Driven by Circ‐CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma

Yanping Wei, Xin Chen, Chi Liang, Yan Ling, Xinwei Yang, Xiaofei Ye, Hailing Zhang, Pinghua Yang, Xiuliang Cui, Yibing Ren, Xianglei Xin, Hengyu Li, Ruoyu Wang, Wenjing Wang, Feng Jiang, Suiyi Liu, Jing Ding, Baohua Zhang, Liang Li, Hongyang Wang – 30 May 2019 – Hepatocellular carcinoma (HCC) is one of the fastest‐rising causes of cancer‐related death worldwide, but its deficiency of specific biomarkers and therapeutic targets in the early stages lead to severe inadequacy in the early diagnosis and treatment of HCC.

Long Noncoding RNA p53‐Stabilizing and Activating RNA Promotes p53 Signaling by Inhibiting Heterogeneous Nuclear Ribonucleoprotein K deSUMOylation and Suppresses Hepatocellular Carcinoma

Geng Qin, Xinyi Tu, Haibei Li, Pengbo Cao, Xi Chen, Jin Song, Hui Han, Yuanfeng Li, Bingqian Guo, Liting Yang, Pandeng Yan, Peiyao Li, Chengming Gao, Jinxu Zhang, Ying Yang, Jian Zheng, Huai‐qiang Ju, Lei Lu, Xuan Wang, Chaohui Yu, Yi Sun, Baocai Xing, Hongzan Ji, Dongxin Lin, Fuchu He, Gangqiao Zhou – 30 May 2019 – To identify hepatocellular carcinoma (HCC)‐implicated long noncoding RNAs (lncRNAs), we performed an integrative omics analysis by integrating mRNA and lncRNA expression profiles in HCC tissues. We identified a collection of candidate HCC‐implicated lncRNAs.

Hepatology Highlights

Jaspreet S. Suri, Ghideon Ezaz, Daryl T.Y. Lau, Tasha B. Kulai, Harmeet Malhi, Zaid H. Tafesh, Brett Fortune, Russell Rosenblatt, Robert S. Brown, Joseph F. Pisa, Nicholas Russo, Petra Hirsova, Robert E. Schwartz, Sayed Obaidullah Aseem, Nidhi Jalan‐Sakrikar, Vikas Gupta – 29 May 2019

Subscribe to