Wenchen Pu, Jiao Li, Yuanyuan Zheng, Xianyan Shen, Xin Fan, Jian‐Kang Zhou, Juan He, Yulan Deng, Xuesha Liu, Chun Wang, Shengyong Yang, Qiang Chen, Lunxu Liu, Guolin Zhang, Yu‐Quan Wei, Yong Peng – 30 January 2018 – Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, but there are few effective treatments. Aberrant microRNA (miRNA) biogenesis is correlated with HCC development. We previously demonstrated that peptidyl‐prolyl cis‐trans isomerase NIMA‐interacting 1 (Pin1) participates in miRNA biogenesis and is a potential HCC treatment target.

Adrien Guillot, Imène Gasmi, Arthur Brouillet, Yeni Ait‐Ahmed, Julien Calderaro, Isaac Ruiz, Bin Gao, Sophie Lotersztajn, Jean‐Michel Pawlotsky, Fouad Lafdil – 30 January 2018 – Liver progenitor cells (LPCs)/ductular reactions (DRs) are associated with inflammation and implicated in the pathogenesis of chronic liver diseases. However, how inflammation regulates LPCs/DRs remains largely unknown. Identification of inflammatory processes that involve LPC activation and expansion represent a key step in understanding the pathogenesis of liver diseases.

Hubert P. J. van der Doef, Patrick F. van Rheenen, Marieke van Rosmalen, Xavier Rogiers, Henkjan J. Verkade, for pediatric liver transplantation centers of Eurotransplant – 29 January 2018 – Liver transplantation (LT) is the standard treatment for biliary atresia (BA) patients with end‐stage liver disease. The prognosis after LT has steadily improved, but overall prognosis of BA patients is also determined by mortality before LT.

David Pereyra, Patrick Starlinger – 29 January 2018

Andrea Kristina Horst, Claudia Wegscheid, Christoph Schaefers, Birgit Schiller, Katrin Neumann, Sebastian Lunemann, Annika E. Langeneckert, Karl J. Oldhafer, Christina Weiler‐Normann, Karl S. Lang, Bernhard B. Singer, Marcus Altfeld, Linda Diehl, Gisa Tiegs – 29 January 2018 – A dysbalance between effector T cells (Tconv) and regulatory T cells (Tregs) and impaired Treg function can cause autoimmune liver disease. Therefore, it is important to identify molecular mechanisms that control Treg homeostasis.

Lorenzo Ridola, Oliviero Riggio – 29 January 2018

29 January 2018

Qing Pang, Huichun Liu, Hao Jin, Lei Zhou, Zhongran Man – 29 January 2018

Lisa I. Backus, Pamela S. Belperio, Troy A. Shahoumian, Larry A. Mole – 29 January 2018 – The impact of sustained virologic response (SVR) on mortality after direct‐acting antiviral (DAA) treatment is not well documented in patients without advanced liver disease and affects access to treatment. This study evaluated the impact of SVR achieved with interferon‐free DAA treatment on all‐cause mortality in hepatitis C virus–infected patients without advanced liver disease.

Heng Fan, Jian‐hua Zhu – 29 January 2018