The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice: A Public Health Perspective
Saumya Pandey – 4 August 2018
Saumya Pandey – 4 August 2018
Ling Yang, Weijun Wang, Xiaozhan Wang, Jinfang Zhao, Li Xiao, Wenfang Gui, Huiqian Fan, Jing Xia, Zhonglin Li, Jingjing Yan, Afnan Alasbahi, Qingjing Zhu, Xiaohua Hou – 4 August 2018 – Hepatic ischemia/reperfusion (I/R) is a major challenge for liver surgery and specific severe conditions of chronic liver disease. Current surgical and pharmacological strategies are limited to improve liver function after hepatic I/R injury. Thus, an in‐depth understanding of the liver I/R mechanism is pivotal to develop new therapeutic methods.
Vinod Arora, Rakhi Maiwall, Vijayaraghavan Rajan, Ankur Jindal, Saggere Muralikrishna Shasthry, Guresh Kumar, Priyanka Jain, Shiv Kumar Sarin – 3 August 2018 – Hepatorenal syndrome (HRS) carries a high short‐term mortality in patients with cirrhosis and acute on chronic liver failure (ACLF). Terlipressin and noradrenaline are routinely used in cirrhosis with HRS and have been found to be equally effective. There are no data comparing the efficacy of terlipressin with noradrenaline in ACLF patients with HRS.
Noelle M. Gorgis, Curtis Kennedy, Fong Lam, Kathleen Thompson, Jorge Coss‐Bu, Ayse Akcan Arikan, Trung Nguyen, Kathleen Hosek, Tamir Miloh, Saul J. Karpen, Daniel J. Penny, John Goss, Moreshwar S. Desai – 3 August 2018 – Cirrhotic cardiomyopathy (CCM), a comorbidity of end‐stage cirrhotic liver disease, remains uncharacterized in children, largely because of a lack of an established pediatric definition.
Noelle M. Gorgis, Curtis Kennedy, Fong Lam, Kathleen Thompson, Jorge Coss‐Bu, Ayse Akcan Arikan, Trung Nguyen, Kathleen Hosek, Tamir Miloh, Saul J. Karpen, Daniel J. Penny, John Goss, Moreshwar S. Desai – 3 August 2018 – Cirrhotic cardiomyopathy (CCM), a comorbidity of end‐stage cirrhotic liver disease, remains uncharacterized in children, largely because of a lack of an established pediatric definition.
Norihiro Imai, David E. Cohen – 3 August 2018
Zobair M. Younossi – 2 August 2018 – Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) can progress to cirrhosis, hepatocellular carcinoma (HCC), death, or liver transplantation. NASH has also been associated with impaired health‐related quality of life and poses a significant economic burden.
Long‐Zi Liu, Zhao Zhang, Bo‐Hao Zheng, Yang Shi, Men Duan, Li‐Jie Ma, Zhi‐Chao Wang, Liang‐Qing Dong, Ping‐Ping Dong, Jie‐Yi Shi, Shu Zhang, Zhen‐Bin Ding, Ai‐Wu Ke, Ya Cao, Xiao‐Ming Zhang, Ruibin Xi, Jian Zhou, Jia Fan, Xiao‐Ying Wang, Qiang Gao – 2 August 2018 – Chemokines play a key role in orchestrating the recruitment and positioning of myeloid cells within the tumor microenvironment. However, the tropism regulation and functions of these cells in hepatocellular carcinoma (HCC) are not completely understood.
Keisaku Sato, Marco Marzioni, Fanyin Meng, Heather Francis, Shannon Glaser, Gianfranco Alpini – 2 August 2018 – Ductular reaction (DR) is characterized by the proliferation of reactive bile ducts induced by liver injuries. DR is pathologically recognized as bile duct hyperplasia and is commonly observed in biliary disorders. It can also be identified in various liver disorders including nonalcoholic fatty liver disease. DR is associated with liver fibrosis and damage, and the extent of DR parallels to patient mortality.
Ji Hye Min, Jong Man Kim, Young Kon Kim, Tae Wook Kang, Soon Jin Lee, Gyu Seong Choi, Seo‐Youn Choi, Soohyun Ahn – 2 August 2018 – We intraindividually compared the efficacy of magnetic resonance imaging (MRI) with extracellular contrast agents (ECA‐MRI) and MRI with hepatobiliary agents (HBA‐MRI) for the diagnosis of hepatocellular carcinoma (HCC) using the Liver Imaging Reporting and Data System (LI‐RADS).