Check your microbiota when taking the drug
Katrin Hochrath, Bernd Schnabl – 6 August 2017
Liver transplantation: Rejection and tolerance
Timucin Taner – 5 August 2017
Pushing the donor limits: Deceased donor liver transplantation using organs from octogenarian donors
Francia Díaz Jaime, Marina Berenguer – 5 August 2017
Longterm outcome of the liver graft: A clinician's perspective—recurrent disease, the universal shifting
Simone I. Strasser – 5 August 2017
Trajectory of adherence behavior in pediatric and adolescent liver transplant recipients: The medication adherence in children who had a liver transplant cohort
Eyal Shemesh, Sarah Duncan, Ravinder Anand, Benjamin L. Shneider, Estella M. Alonso, George V. Mazariegos, Robert S. Venick, Rachel A. Annunziato, John C. Bucuvalas – 5 August 2017 – Knowledge of the longterm trajectory of nonadherence to immunosuppressants can inform decisions regarding organ allocation, adherence monitoring, and intervention efforts.
Extreme large‐for‐size syndrome after adult liver transplantation: A model for predicting a potentially lethal complication
Marc‐Antoine Allard, Felipe Lopes, Fabio Frosio, Nicolas Golse, Antonio Sa Cunha, Daniel Cherqui, Denis Castaing, René Adam, Eric Vibert – 5 August 2017 – There is currently no tool available to predict extreme large‐for‐size (LFS) syndrome, a potentially disastrous complication after adult liver transplantation (LT). We aimed to identify the risk factors for extreme LFS and to build a simple predictive model. A cohort of consecutive patients who underwent LT with full grafts in a single institution was studied.
Bile duct regeneration and immune response by passenger lymphocytes signals biliary recovery versus complications after liver transplantation
Henrik H. Junger, Hans J. Schlitt, Edward K. Geissler, Stefan Fichtner‐Feigl, Stefan M. Brunner – 5 August 2017 – This study aimed to elucidate the impact of epithelial regenerative responses and immune cell infiltration on biliary complications after liver transplantation. Bile duct (BD) damage after cold storage was quantified by a BD damage score and correlated with patient outcome in 41 patients. Bacterial infiltration was determined by fluorescence in situ hybridization (FISH).
Utilization of hepatitis C virus RNA–positive donor liver for transplant to hepatitis C virus RNA–negative recipient
Behnam Saberi, James P. Hamilton, Christine M. Durand, Zhiping Li, Benjamin Philosophe, Andrew M. Cameron, Mark S. Sulkowski, Ahmet Gurakar – 5 August 2017
Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice
Michitaka Matsuda, Shinya Tsurusaki, Naoko Miyata, Eiko Saijou, Hitoshi Okochi, Atsushi Miyajima, Minoru Tanaka – 5 August 2017 – Fibrosis is an important wound‐healing process in injured tissues, but excessive fibrosis is often observed in patients with chronic inflammation. Although oncostatin M (OSM) has been reported to play crucial roles for recovery from acute liver injury by inducing tissue inhibitor of metalloproteinase 1 (Timp1) expression, the role of OSM in chronic liver injury (CLI) is yet to be elucidated.
The contribution of health risk behaviors to excess mortality in American adults with chronic hepatitis C: A population cohort‐study
Hamish Innes, Andrew McAuley, Maryam Alavi, Heather Valerio, David Goldberg, Sharon J. Hutchinson – 4 August 2017 – In resource‐rich countries, chronic hepatitis C (CHC) infection is associated with a sizeable excess mortality risk. The extent to which this is due to (1) the biological sequelae of CHC infection versus (2) a high concomitant burden of health risk behaviors (HRBs) is unclear. We used data from the 1999‐2010 U.S. National Health and Nutritional Examination Surveys (NHANES), which include detailed information on HRBs and CHC infection status.