Complexity and function of natural killer T cells with potential application to hepatic transplant survival
Randle Ware, Vipin Kumar – 25 September 2017 – One of the major innate‐like lymphocyte populations enriched in the liver consists of natural killer T (NKT) cells, which recognize self and foreign lipid antigens presented by the nonpolymorphic class I major histocompatibility complex–like molecule CD1d. NKT cells express natural killer cell markers as well as T cell receptors (TCRs) and can be classified into 2 categories: type I NKT cells use a semi‐invariant TCR, whereas type II NKT cells express diverse but still limited TCRs.