Regulation of retinol‐binding protein 4 and retinol metabolism in fatty liver disease
Stefano Romeo, Luca Valenti – 11 July 2016
Pseudocirrhosis and liver failure in patients with metastatic breast cancer after treatment with palbociclib
Raj Vuppalanchi, Romil Saxena, Anna Maria V. Storniolo, Naga Chalasani – 11 July 2016
Combined systemic elimination of MET and epidermal growth factor receptor signaling completely abolishes liver regeneration and leads to liver decompensation
Shirish Paranjpe, William C. Bowen, Wendy M. Mars, Anne Orr, Meagan M. Haynes, Marie C. DeFrances, Silvia Liu, George C. Tseng, Anastasia Tsagianni, George K. Michalopoulos – 11 July 2016 – Receptor tyrosine kinases MET and epidermal growth factor receptor (EGFR) are critically involved in initiation of liver regeneration. Other cytokines and signaling molecules also participate in the early part of the process. Regeneration employs effective redundancy schemes to compensate for the missing signals.
IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell‐death mediator receptor‐interacting protein kinase 1
Christiane Koppe, Patricia Verheugd, Jérémie Gautheron, Florian Reisinger, Karina Kreggenwinkel, Christoph Roderburg, Luca Quagliata, Luigi Terracciano, Nikolaus Gassler, René H. Tolba, Yannick Boege, Achim Weber, Michael Karin, Mark Luedde, Ulf P.
Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo
Natalie Porat‐Shliom, Amber J. Tietgens, Christina M. Itallie, Lynn Vitale‐Cross, Michal Jarnik, Olivia J. Harding, James M. Anderson, J. Silvio Gutkind, Roberto Weigert, Irwin M. Arias – 11 July 2016 – Liver kinase B1 (LKB1) and its downstream effector AMP‐activated protein kinase (AMPK) play critical roles in polarity establishment by regulating membrane trafficking and energy metabolism. In collagen sandwich‐cultured hepatocytes, loss of LKB1 or AMPK impaired apical ABCB11 (Bsep) trafficking and bile canalicular formation.
Strategies to improve outcomes for hepatitis C virus/human immunodeficiency virus coinfected liver transplant candidates
Garrett R. Roll, Peter G. Stock – 8 July 2016
Balancing quality with quantity: The role of palliative care in managing decompensated cirrhosis
Karl M. Langberg, Tamar H. Taddei – 7 July 2016
Nonalcoholic Fatty Liver Disease: Epidemiology, Natural History, and Diagnostic Challenges
George Cholankeril, Ryan B. Perumpail, Edward A. Pham, Aijaz Ahmed, Stephen A. Harrison – 7 July 2016
Withdrawal of posttransplant hepatitis B virus prophylaxis: A blind test
Bruno Roche, Didier Samuel – 7 July 2016
Hypothalamic kappa opioid receptor mediates both diet‐induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress
Monica Imbernon, Estrella Sanchez‐Rebordelo, Amparo Romero‐Picó, Imre Kalló, Melissa J. Chee, Begoña Porteiro, Omar Al‐Massadi, Cristina Contreras, Johan Fernø, Ana Senra, Rosalia Gallego, Cintia Folgueira, Luisa M. Seoane, Margriet van Gestel, Roger A. Adan, Zsolt Liposits, Carlos Dieguez, Miguel López, Ruben Nogueiras – 7 July 2016 – The opioid system is widely known to modulate the brain reward system and thus affect the behavior of humans and other animals, including feeding. We hypothesized that the hypothalamic opioid system might also control energy metabolism in peripheral tissues.