Frank Tacke, Daniela C. Kroy, Ana Paula Barreiros, Ulf P. Neumann – 15 April 2016 – Liver transplantation (LT) is a well‐accepted procedure for end‐stage liver disease in Germany. In 2015, 1489 patients were admitted to the waiting list (including 1308 new admissions), with the leading etiologies being fibrosis and cirrhosis (n = 349), alcoholic liver disease (n = 302), and hepatobiliary malignancies (n = 220). Organ allocation in Germany is regulated within the Eurotransplant system based on urgency as expressed by the Model for End‐Stage Liver Disease score.

Amelia J. Hessheimer, Andrés Cárdenas, Juan C. García‐Valdecasas, Constantino Fondevila – 15 April 2016 – The pool of livers for transplantation consists of an increasingly greater proportion of marginal grafts, in particular those arising through donation after circulatory determination of death (DCD). However, a primary factor limiting the use of marginal livers, and, thereby, the applicability of liver transplantation in general, is concern over the subsequent development of ischemic‐type biliary lesion (ITBL).

Gomathy Narasimhan, Venugopal Kota, Mohamed Rela – 15 April 2016 – Liver transplantation as an established form of treatment for end‐stage liver disease has gained acceptance in India over the last 10 years. Liver transplantation in India has unique features that have contributed to the growth of both deceased donor and living donor transplantations of which living donor currently dominates the picture. Living donor contributes to 80% and deceased donor to 20% of the liver transplants currently performed in India.

Orith Waisbourd‐Zinman, Hong Koh, Shannon Tsai, Pierre‐Marie Lavrut, Christine Dang, Xiao Zhao, Michael Pack, Jeff Cave, Mark Hawes, Kyung A. Koo, John R. Porter, Rebecca G. Wells – 15 April 2016 – Biliary atresia, the most common indication for pediatric liver transplantation, is a fibrotic disease of unknown etiology affecting the extrahepatic bile ducts of newborns. The recently described toxin biliatresone causes lumen obstruction in mouse cholangiocyte spheroids and represents a new model of biliary atresia.

Lise L. Gluud, Hendrik Vilstrup, Marsha Y. Morgan – 15 April 2016 – Nonabsorbable disaccharides (NADs) have been used to treat hepatic encephalopathy (HE) since 1966. However, a Cochrane Review, published in 2004, found insufficient evidence to recommend their use in this context. This updated systematic review evaluates the effects of the NADs, lactulose and lactitol, for the treatment and prevention of HE in patients with cirrhosis.

Sarah Sheibani, Saro Khemichian, John J. Kim, Linda Hou, Arthur W. Yan, James Buxbaum, Lily Dara, Loren Laine – 15 April 2016 – The appropriate interval between ligation sessions for treatment of esophageal variceal bleeding is uncertain. The optimal interval would provide variceal eradication as rapidly as possible to lessen early rebleeding while minimizing ligation‐induced adverse events. We randomly assigned patients hospitalized with acute esophageal variceal bleeding who had successful ligation at presentation to repeat ligation at 1‐week or 2‐week intervals.

Adam X. Sang, Aleishia Harris‐Arnold, Neeraja Kambham, Olivia M. Martinez, Sheri M. Krams, Debra Strichartz, Carlos O. Esquivel – 11 April 2016

Pratima Sharma, Neehar D. Parikh, Jessica Yu, Pranab Barman, Brian A. Derstine, Christopher J. Sonnenday, Stewart C. Wang, Grace L. Su – 11 April 2016 – Hepatocellular carcinoma (HCC) is a common indication for liver transplantation (LT). Recent data suggest that body composition features strongly affect post‐LT mortality. We examined the impact of body composition on post‐LT mortality in patients with HCC.

Masood Iqbal, Elgaily A. Elrayah, Oscar Traynor, P. Aiden McCormick – 11 April 2016 – The Irish National Liver Transplant program commenced in 1993 in St. Vincent's University Hospital in Dublin. It is an adult‐only program and is the only liver transplant program in Ireland. Pediatric recipients are referred to King's College Hospital in the United Kingdom. To date, almost 1000 adult liver transplants have been performed. Current 1‐year patient survival is 93%, and 5‐year survival is 79%. The program is fully funded by the government health service.

Vincent Wai‐Sun Wong, Grace Lai‐Hung Wong, Henry Lik‐Yuen Chan – 8 April 2016