Liver transplantation in Australia and New Zealand

Geoffrey W. McCaughan, Stephen R. Munn – 30 March 2016 – Liver transplantation (LT) in Australia and New Zealand began in 1985. Over this time until December 2014, LT took place in 3700 adults and 800 children. LT is regulated with 1 unit, supported by the government, per state or region. Currently approximately 270 transplants take place per year. Organ donation rates are moderate in Australia (17 per 1 million of population) but very low in New Zealand (11 per 1 million of population). All the units share organ donors for fulminant hepatic failure cases (status 1).

Role of patient factors, preferences, and distrust in health care and access to liver transplantation and organ donation

Julius M. Wilder, Omobonike O. Oloruntoba, Andrew J. Muir, Cynthia A. Moylan – 30 March 2016 – Despite major improvements in access to liver transplantation (LT), disparities remain. Little is known about how distrust in medical care, patient preferences, and the origins shaping those preferences contribute to differences surrounding access. We performed a single‐center, cross‐sectional survey of adults with end‐stage liver disease and compared responses between LT listed and nonlisted patients as well as by race.

Role of ammonia, inflammation, and cerebral oxygenation in brain dysfunction of acute‐on‐chronic liver failure patients

Rohit Sawhney, Peter Holland‐Fischer, Matteo Rosselli, Rajeshwar P. Mookerjee, Banwari Agarwal, Rajiv Jalan – 30 March 2016 – Hepatic encephalopathy (HE) is a common feature of acute‐on‐chronic liver failure (ACLF). Although ammonia, inflammation, and cerebral oxygenation are associated with HE in acute liver failure, their roles in ACLF are unknown. The aim of this prospective, longitudinal study was to determine the role of these pathophysiological variables in ACLF patients with and without HE. We studied 101 patients with ACLF admitted to the intensive care unit.

Longterm results of liver transplantation from donation after circulatory death

Joris J. Blok, Olivier Detry, Hein Putter, Xavier Rogiers, Robert J. Porte, Bart van Hoek, Jacques Pirenne, Herold J. Metselaar, Jan P. Lerut, Dirk K. Ysebaert, Valerio Lucidi, Roberto I. Troisi, Undine Samuel, A. Claire den Dulk, Jan Ringers, Andries E. Braat, for the Eurotransplant Liver Intestine Advisory Committee – 30 March 2016 – Donation after circulatory death (DCD) liver transplantation (LT) may imply a risk for decreased graft survival, caused by posttransplantation complications such as primary nonfunction or ischemic‐type biliary lesions.

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