High prevalence of hepatic fibrosis in the setting of coexisting diabetes and hepatic steatosis: A case for selective screening in the general population?
Aijaz Ahmed, Ryan B. Perumpail, Stephen A. Harrison – 9 October 2015
Time to Abandon NASH?
Jean‐François Dufour – 9 October 2015
Prevalence of hepatitis delta infection in the United States: National Health and Nutrition Examination Survey, 1999‐2012
Basile Njei, Albert Do, Joseph K. Lim – 9 October 2015
NASH, from diagnosis to treatment: Where do we stand?
Stephen A. Harrison – 8 October 2015
Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis
Zhen‐Wei Peng, Naoki Ikenaga, Susan B. Liu, Deanna Y. Sverdlov, Kahini A. Vaid, Richa Dixit, Paul H. Weinreb, Shelia Violette, Dean Sheppard, Detlef Schuppan, Yury Popov – 8 October 2015 – Integrin αvβ6 is rapidly up‐regulated on cells of epithelial lineage during tissue injury, where one of its primary functions is activation of latent transforming growth factor beta 1 (TGFβ1). In human liver cirrhosis, αvβ6 is overexpressed by cells comprising the ductular reaction, and its inhibition suppresses experimental biliary fibrosis in rodents.
Parallel 33: Drug Metabolism and Toxicity
7 October 2015