DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration

Kosuke Kaji, Valentina M. Factor, Jesper B. Andersen, Marian E. Durkin, Akira Tomokuni, Jens U. Marquardt, Matthias S. Matter, Tanya Hoang, Elizabeth A. Conner, Snorri S. Thorgeirsson – 21 March 2016 – DNA methyltransferase 1 (DNMT1) is an essential regulator maintaining both epigenetic reprogramming during DNA replication and genome stability. We investigated the role of DNMT1 in the regulation of postnatal liver histogenesis under homeostasis and stress conditions.

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