Targeting the Achilles' heel of adult living donor liver transplant: Corner‐sparing sutures with mucosal eversion technique of biliary anastomosis

Vivek Vij, Kausar Makki, Vishal Kumar Chorasiya, Gaurav Sood, Ashish Singhal, Puneet Dargan – 21 September 2015 – Biliary complications are regarded as the Achilles' heel of liver transplantation, especially for living donor liver transplantation (LDLT) due to smaller, multiple ducts and difficult ductal anatomy. Overall biliary complications reported in most series are between 10% and 30%. This study describes our modified technique of biliary anastomosis and its effects on incidence of biliary complications.

Predictors of hepatitis B e antigen‐negative hepatitis in chronic hepatitis B virus‐infected patients from childhood to adulthood

Jia‐Feng Wu, Yu‐Chun Chiu, Kai‐Chi Chang, Huey‐Ling Chen, Yen‐Hsuan Ni, Hong‐Yuan Hsu, Mei‐Hwei Chang – 21 September 2015 – Hepatitis B e antigen (HBeAg)‐negative hepatitis is a clinical indicator of poor outcome for chronic hepatitis B viral (HBV) infection. This long‐term prospective cohort study aimed to elucidate the predictors of developing HBeAg‐negative hepatitis in chronic HBV‐infected subjects followed from childhood to adulthood. We followed 434 HBeAg‐positive chronic HBV‐infected patients from a median age of 7.22 years (interquartile range 4.31‐10.21 years).

Split liver transplantation: Report of right and left graft outcomes from a multicenter Argentinean group

Esteban Halac, Marcelo Dip, Emilio Quiñonez, Fernando Alvarez, Johana Leiva Espinoza, Pablo Romero, Franco Nievas, Rafael Maurette, Carlos Luque, Daniel Matus, Paz Surraco, Martin Fauda, Lucas McCormack, Francisco J. Mattera, Gabriel Gondolesi, Oscar Imventarza – 15 September 2015 – Grafts from split livers (SLs) constitute an accepted approach to expand the donor pool. Over the last 5 years, most Argentinean centers have shown significant interest in increasing the use of this technique.

Natural killer cell phenotype modulation and natural killer/T‐cell interplay in nucleos(t)ide analogue‐treated hepatitis e antigen‐negative patients with chronic hepatitis B

Carolina Boni, Pietro Lampertico, Lavinia Talamona, Tiziana Giuberti, Federica Invernizzi, Valeria Barili, Paola Fisicaro, Marzia Rossi, Maria Cristina Cavallo, Andrea Vecchi, Giuseppe Pedrazzi, Arianna Alfieri, Massimo Colombo, Gabriele Missale, Carlo Ferrari – 11 September 2015 – Natural killer (NK) and hepatitis B virus (HBV)‐specific T cells are functionally impaired in chronic hepatitis B (CHB).

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