Outflow reconstruction for right liver allograft with multiple hepatic veins: “V‐plasty” of hepatic veins to form a common outflow channel versus 2 or more hepatic vein–to–inferior vena cava anastomoses in limited retrohepatic space

Ashok Thorat, Long‐Bin Jeng, Horng‐Ren Yang, Ping‐Chun Li, Ming‐Li Li, Chun‐Chieh Yeh, Te‐Hung Chen, Shih‐Chao Hsu, Kin‐Shing Poon – 21 September 2015 – Outflow reconstruction in living donor liver transplantation (LDLT) is certainly difficult in limited retrohepatic space with using right liver grafts with venous anomalies. Venoplasty of the inferior right hepatic veins (IRHVs) and middle hepatic vein (MHV) reconstruction using synthetic grafts to form a common outflow channel or a second venocaval anastomosis are available options.

Prevention of hepatitis C virus infection using a broad cross‐neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate

Daire O'Shea, John Law, Adrian Egli, Donna Douglas, Gary Lund, Sarah Forester, Joshua Lambert, Mansun Law, Dennis R. Burton, D. L. J. Tyrrell, Michael Houghton, Atul Humar, Norman Kneteman – 21 September 2015 – The anti–hepatitis C virus (HCV) activity of a novel monoclonal antibody (mAb; AR4A) and epigallocatechin gallate (EGCG) were studied in vitro using a HCV cell culture system and in vivo using a humanized liver mouse model capable of supporting HCV replication.

Yes‐associated protein 1 and transcriptional coactivator with PDZ‐binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma

Yun‐Yong Park, Bo Hwa Sohn, Randy L. Johnson, Myoung‐Hee Kang, Sang Bae Kim, Jae‐Jun Shim, Lingegowda S. Mangala, Ji Hoon Kim, Jeong Eun Yoo, Cristian Rodriguez‐Aguayo, Sunila Pradeep, Jun Eul Hwang, Hee‐Jin Jang, Hyun‐Sung Lee, Rajesha Rupaimoole, Gabriel Lopez‐Berestein, Woojin Jeong, Inn Sun Park, Young Nyun Park, Anil K. Sood, Gordon B. Mills, Ju‐Seog Lee – 21 September 2015 – Metabolic activation is a common feature of many cancer cells and is frequently associated with the clinical outcomes of various cancers, including hepatocellular carcinoma.

Split liver transplantation: Report of right and left graft outcomes from a multicenter Argentinean group

Esteban Halac, Marcelo Dip, Emilio Quiñonez, Fernando Alvarez, Johana Leiva Espinoza, Pablo Romero, Franco Nievas, Rafael Maurette, Carlos Luque, Daniel Matus, Paz Surraco, Martin Fauda, Lucas McCormack, Francisco J. Mattera, Gabriel Gondolesi, Oscar Imventarza – 15 September 2015 – Grafts from split livers (SLs) constitute an accepted approach to expand the donor pool. Over the last 5 years, most Argentinean centers have shown significant interest in increasing the use of this technique.

Conversion of once‐daily extended‐release tacrolimus is safe in stable liver transplant recipients: A randomized prospective study

Jong Man Kim, Choon Hyuck David Kwon, Jae‐Won Joh, Dong Hyun Sinn, Sanghoon Lee, Gyu‐Seong Choi, Suk‐Koo Lee – 11 September 2015 – Simplifying the therapeutic regimen of liver transplantation (LT) recipients may help prevent acute rejection and graft failure. The present study aimed to evaluate the efficacy and safety of conversion from twice‐daily tacrolimus to once‐daily extended‐release tacrolimus under concurrent mycophenolate mofetil therapy in stable LT recipients.

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