Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure

Rashi Sehgal, Sharda Patra, Paul David, Ashish Vyas, Arshi Khanam, Syed Hissar, Ekta Gupta, Guresh Kumar, Shyam Kottilil, Rakhi Maiwall, Shiv Kumar Sarin, Nirupama Trehanpati – 31 August 2015 – Acute viral hepatitis resulting due to hepatitis E viral infection (AVH‐E) is often serious in pregnancy and could result in acute liver failure (ALF). The role of monocytes and macrophages (mono‐macs) in the pathogenesis of AVH‐E and development of ALF‐E in pregnancy is unclear.

Longterm health‐related quality of life after living liver donation

Vanessa R. Humphreville, David M. Radosevich, Abhinav Humar, William D. Payne, Raja Kandaswamy, John R. Lake, Arthur J. Matas, Timothy L. Pruett, Srinath Chinnakotla – 31 August 2015 – There are little data on longterm outcomes, health‐related quality of life (HRQoL), and issues related to living donor right hepatectomy specifically. We studied longterm HRQoL in 127 living liver donors.

Physical activity and liver diseases

Annalisa Berzigotti, Uttara Saran, Jean‐François Dufour – 27 August 2015 – Regular physical activity beneficially impacts the risk of onset and progression of several chronic diseases. However, research regarding the effects of exercising on chronic liver diseases is relatively recent. Most researchers focused on nonalcoholic fatty liver disease (NAFLD), in which increasing clinical and experimental data indicate that skeletal muscle crosstalking to the adipose tissue and the liver regulates intrahepatic fat storage.

Physical activity and liver diseases

Annalisa Berzigotti, Uttara Saran, Jean‐François Dufour – 27 August 2015 – Regular physical activity beneficially impacts the risk of onset and progression of several chronic diseases. However, research regarding the effects of exercising on chronic liver diseases is relatively recent. Most researchers focused on nonalcoholic fatty liver disease (NAFLD), in which increasing clinical and experimental data indicate that skeletal muscle crosstalking to the adipose tissue and the liver regulates intrahepatic fat storage.

Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis

Judit López‐Luque, Daniel Caballero‐Díaz, Adoración Martinez‐Palacián, César Roncero, Joaquim Moreno‐Càceres, María García‐Bravo, Esther Grueso, Almudena Fernández, Eva Crosas‐Molist, María García‐Álvaro, Annalisa Addante, Esther Bertran, Angela M. Valverde, Águeda González‐Rodríguez, Blanca Herrera, Lluis Montoliu, Teresa Serrano, Jose‐Carlos Segovia, Margarita Fernández, Emilio Ramos, Aránzazu Sánchez, Isabel Fabregat – 27 August 2015 – Different data support a role for the epidermal growth factor receptor (EGFR) pathway during liver regeneration and hepatocarcinogenesis.

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