Thrombelastography‐guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: A randomized, controlled trial

Lesley De Pietri, Marcello Bianchini, Roberto Montalti, Nicola De Maria, Tommaso Di Maira, Bruno Begliomini, Giorgio Enrico Gerunda, Fabrizio di Benedetto, Guadalupe Garcia‐Tsao, Erica Villa – 4 September 2015 – Bleeding is a feared complication of invasive procedures in patients with cirrhosis and significant coagulopathy (as defined by routine coagulation tests) and is used to justify preprocedure use of fresh frozen plasma (FFP) and/or platelets (PLT).

Prognosis of acute variceal bleeding: Is being on beta‐blockers an aggravating factor? A short‐term survival analysis

Andrea Ribeiro de Souza, Vincenzo La Mura, Annalisa Berzigotti, Juan Carlos García‐Pagán, Juan G. Abraldes, Jaime Bosch – 4 September 2015 – Nonselective beta‐blockers (NSBB) are widely used because they have been proved effective in the prophylaxis of acute variceal bleeding (AVB). However, a significant proportion of patients still experience AVB while on treatment with NSBB, and its impact on prognosis of AVB is unknown.

Impact of donor age in liver transplantation from donation after circulatory death donors: A decade of experience at Cleveland Clinic

Daniel J. Firl, Koji Hashimoto, Colin O'Rourke, Teresa Diago‐Uso, Masato Fujiki, Federico N. Aucejo, Cristiano Quintini, Dympna M. Kelly, Charles M. Miller, John J. Fung, Bijan Eghtesad – 3 September 2015 – The use of liver grafts from donation after circulatory death (DCD) donors remains controversial, particularly with donors of advanced age. This retrospective study investigated the impact of donor age in DCD liver transplantation.

Using ultrasonography to monitor liver blood flow for liver transplant from donors supported on extracorporeal membrane oxygenation

Xian‐Sheng Zhu, Sha‐Sha Wang, Qi Cheng, Chuang‐Wen Ye, Feng Huo, Peng Li – 3 September 2015 – Extracorporeal membrane oxygenation (ECMO) has been used to support brain‐dead donors for liver procurement. This study investigated the potential role of ultrasonographic monitoring of hepatic perfusion as an aid to improve the viability of liver transplants obtained from brain‐dead donors who are supported on ECMO. A total of 40 brain‐dead patients maintained on ECMO served as the study population.

Living donor liver transplantation using dual grafts: Experience and lessons learned from cases worldwide

Yinzhe Xu, Hao Chen, Heidi Yeh, Hongguang Wang, Jianjun Leng, Jiahong Dong – 3 September 2015 – In living donor liver transplantation (LDLT), insufficient graft volume could result in small‐for‐size syndrome in recipients, whereas major liver donation predisposes the donor to a high risk of posthepatectomy liver failure. Dual graft LDLT is therefore introduced to obtain combined graft sufficiency. To date, 367 patients have been reported worldwide. We reviewed all the relevant literature, with a special focus on 43 case reports containing enough data to extract and analyze.

Characteristics and outcomes of neutropenia after orthotopic liver transplantation

Basem Alraddadi, Natalie E. Nierenberg, Lori Lyn Price, Jennifer K. L. Chow, Debra D. Poutsiaka, Richard J. Rohrer, Jeffrey T. Cooper, Richard B. Freeman, David R. Snydman – 3 September 2015 – Neutropenia after orthotopic liver transplantation (LT) is relatively common, but the factors associated with its development remain elusive.

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