Using ultrasonography to monitor liver blood flow for liver transplant from donors supported on extracorporeal membrane oxygenation

Xian‐Sheng Zhu, Sha‐Sha Wang, Qi Cheng, Chuang‐Wen Ye, Feng Huo, Peng Li – 3 September 2015 – Extracorporeal membrane oxygenation (ECMO) has been used to support brain‐dead donors for liver procurement. This study investigated the potential role of ultrasonographic monitoring of hepatic perfusion as an aid to improve the viability of liver transplants obtained from brain‐dead donors who are supported on ECMO. A total of 40 brain‐dead patients maintained on ECMO served as the study population.

Impact of donor age in liver transplantation from donation after circulatory death donors: A decade of experience at Cleveland Clinic

Daniel J. Firl, Koji Hashimoto, Colin O'Rourke, Teresa Diago‐Uso, Masato Fujiki, Federico N. Aucejo, Cristiano Quintini, Dympna M. Kelly, Charles M. Miller, John J. Fung, Bijan Eghtesad – 3 September 2015 – The use of liver grafts from donation after circulatory death (DCD) donors remains controversial, particularly with donors of advanced age. This retrospective study investigated the impact of donor age in DCD liver transplantation.

The dual and opposite role of the TM6SF2‐rs58542926 variant in protecting against cardiovascular disease and conferring risk for nonalcoholic fatty liver: A meta‐analysis

Carlos J. Pirola, Silvia Sookoian – 1 September 2015 – The aim of this work was to estimate the strength of the effect of the TM6SF2 E167K (rs58542926 C/T) variant on blood lipid traits and nonalcoholic fatty liver disease (NAFLD) across different populations. We performed a systematic review by a meta‐analysis; literature searches identified 10 studies. The rs58542926 exerts a significant role in modulating lipid traits, including total cholesterol (TC), low‐density lipoprotein cholesterol (LDL‐C), triglycerides (TG), and NAFLD.

Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure

Rashi Sehgal, Sharda Patra, Paul David, Ashish Vyas, Arshi Khanam, Syed Hissar, Ekta Gupta, Guresh Kumar, Shyam Kottilil, Rakhi Maiwall, Shiv Kumar Sarin, Nirupama Trehanpati – 31 August 2015 – Acute viral hepatitis resulting due to hepatitis E viral infection (AVH‐E) is often serious in pregnancy and could result in acute liver failure (ALF). The role of monocytes and macrophages (mono‐macs) in the pathogenesis of AVH‐E and development of ALF‐E in pregnancy is unclear.

Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure

Rashi Sehgal, Sharda Patra, Paul David, Ashish Vyas, Arshi Khanam, Syed Hissar, Ekta Gupta, Guresh Kumar, Shyam Kottilil, Rakhi Maiwall, Shiv Kumar Sarin, Nirupama Trehanpati – 31 August 2015 – Acute viral hepatitis resulting due to hepatitis E viral infection (AVH‐E) is often serious in pregnancy and could result in acute liver failure (ALF). The role of monocytes and macrophages (mono‐macs) in the pathogenesis of AVH‐E and development of ALF‐E in pregnancy is unclear.

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