Genetic susceptibility to hepatitis E viral infection: An enigmatic virus gives up a secret
Ivo Ditah, Michael Charlton – 6 August 2015
Validation of hepatitis B virus–related hepatocellular carcinoma prediction models in the era of antiviral therapy
Kyu Sik Jung, Seung Up Kim, Kijun Song, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Beom Kyung Kim, Kwang‐Hyub Han – 6 August 2015 – Several risk prediction models have been created to predict hepatitis B virus (HBV)‐related hepatocellular carcinoma (HCC) occurrence, with promising results. However, their prognostic performances need to be validated in the era of antiviral therapy. From 2006 to 2011, patients with chronic HBV infection were recruited and those with a history of HCC or hepatic decompensation were excluded.
Flunarizine prevents hepatitis C virus membrane fusion in a genotype‐dependent manner by targeting the potential fusion peptide within E1
Paula M. Perin, Sibylle Haid, Richard J.P. Brown, Juliane Doerrbecker, Kai Schulze, Carsten Zeilinger, Markus von Schaewen, Brigitte Heller, Koen Vercauteren, Eva Luxenburger, Yasmine M. Baktash, Florian W.R. Vondran, Sietkse Speerstra, Abdullah Awadh, Furkat Mukhtarov, Luis M. Schang, Andreas Kirschning, Rolf Müller, Carlos A. Guzman, Lars Kaderali, Glenn Randall, Philip Meuleman, Alexander Ploss, Thomas Pietschmann – 6 August 2015 – To explore mechanisms of hepatitis C viral (HCV) replication we screened a compound library including licensed drugs.
Should age matter? A new proposal for liver transplantation allocation
Lisa B. VanWagner, Anton I. Skaro – 6 August 2015
Prevalence of chronic hepatitis B virus (HBV) infection in U.S. households: National Health and Nutrition Examination Survey (NHANES), 1988‐2012
Henry Roberts, Deanna Kruszon‐Moran, Kathleen N. Ly, Elizabeth Hughes, Kashif Iqbal, Ruth B. Jiles, Scott D. Holmberg – 6 August 2015 – The number of persons with chronic hepatitis B virus (HBV) infection in the United States is affected by diminishing numbers of young persons who are susceptible because of universal infant vaccination since 1991, offset by numbers of HBV‐infected persons migrating to the United States from endemic countries.
Severe hepatotoxicity associated with asunaprevir and daclatasvir in chronic hepatitis C
Soichiro Shibata, Takeji Umemura, Michiharu Komatsu, Eiji Tanaka – 6 August 2015
Acute kidney injury after orthotopic liver transplantation using living donor versus deceased donor grafts: A propensity score‐matched analysis
Gang Ma, HaiXia Jiang, XiYang Zhang, Tao Zhu – 6 August 2015
Acetaminophen knocks on death's door and receptor interacting protein 1 kinase answers
Maria Eugenia Guicciardi, Gregory J. Gores, Hartmut Jaeschke – 6 August 2015
High priority for hepatitis C screening in safety net hospitals: Results from a prospective cohort of 4582 hospitalized baby boomers
Barbara J. Turner, Barbara S. Taylor, Joshua Hanson, Yuanyuan Liang, Poornachand Veerapaneni, Roberto Villarreal, Mary Perez, Ludivina Hernandez, Jasdeep Sandhu, Kristin Fiebelkorn – 6 August 2015 – Low‐income populations are disproportionately affected by hepatitis C virus (HCV) infection. Thus, implementing baby boomer screening (born 1945‐1965) for HCV may be a high priority for safety net hospitals.
Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune‐mediated hepatitis
Tomoko Fujita, Kitipong Soontrapa, Yoshiya Ito, Keiko Iwaisako, Catharina Sagita Moniaga, Masataka Asagiri, Masataka Majima, Shuh Narumiya – 6 August 2015 – Hepatic stellate cells (HSCs) constitute the liver sinusoid with Kupffer cells and liver sinusoidal endothelial cells. While the sinusoid functions as the gateway to liver inflammation, whether HSCs contribute to liver inflammation and, if so, how they exert such functions remain elusive. Here, we found that mouse as well as human HSCs expressed DP1 receptor for prostaglandin D2 selectively in the liver.