Long‐term outcome of endovascular intervention in hepatic venous outflow obstruction following pediatric liver transplantation

Jin Woo Choi, Hwan Jun Jae, Hyo‐Cheol Kim, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh, Jin Wook Chung – 22 July 2015 – The purpose of our study was to address the long‐term outcome of angioplasty and stent placement for hepatic venous outflow obstruction following pediatric liver transplantation. From October 1999 to December 2011, 20 stenotic lesions were confirmed to constitute hepatic venous outflow obstruction in 18 pediatric patients (13 boys, 5 girls) among 152 pediatric patients following liver transplantation and were managed with endovascular intervention.

Serum lipid expression correlates with function and regeneration following living donor liver transplantation

Joshua H. Wolf, Michael V. Holmes, Suomi Fouraschen, Brendan J. Keating, Talia Baker, Jean Emond, Daniel J. Rader, Abraham Shaked, Kim M. Olthoff – 22 July 2015 – Following living donor liver transplantation (LDLT; and unlike deceased donor liver transplantation [DDLT]), the liver must rapidly regenerate, and sometimes segmental graft dysfunction (SGD) is observed. Hepatic regeneration requires substantial de novo lipid synthesis, and we previously reported that expression of lipid‐related genes is dysregulated in LDLT.

Imaging the dynamic platelet‐neutrophil response in sterile liver injury and repair in mice

Ingrid Slaba, Jing Wang, Elzbieta Kolaczkowska, Braedon McDonald, Woo‐Yong Lee, Paul Kubes – 22 July 2015 – Although platelets have been extensively studied in hemostasis and inflammation, their role is not well understood in sterile liver injury and repair. Using a thermally induced focal liver injury and repair model and multichannel spinning disk confocal microscopy allowed visualization of the dynamic behavior of platelets and neutrophils in this insult.

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