Mamatha Bhat, Peter Ghali, Kathleen C. Rollet‐Kurhajec, Aparna Bhat, Philip Wong, Marc Deschenes, Giada Sebastiani – 20 July 2015 – Noninvasive serum fibrosis biomarkers predict clinical outcomes in pretransplant patients with chronic liver disease. We investigated the role of serum fibrosis biomarkers and of changes in biomarkers in predicting death and graft loss after liver transplantation (LT).
Siddharth Sood, Craig Haifer, Lijia Yu, Julie Pavlovic, Paul J. Gow, Robert M. Jones, Kumar Visvanathan, Peter W. Angus, Adam G. Testro – 20 July 2015 – Cytomegalovirus (CMV) can reactivate following liver transplantation. Management of patients currently considered low risk based on pretransplant serology remains contentious, with universal prophylaxis and preemptive strategies suffering from significant deficiencies.
Siddharth Singh, Rohan Khera, Alina M. Allen, M. Hassan Murad, Rohit Loomba – 18 July 2015 – We performed a Bayesian network meta‐analysis combining direct and indirect treatment comparisons to assess the comparative effectiveness of pharmacological agents for the treatment of nonalcoholic steatohepatitis (NASH). Through systematic literature review, we identified nine randomized, controlled trials (RCTs) including 964 patients with biopsy‐proven NASH, comparing vitamin E, thiazolidinediones (TZDs), pentoxifylline, or obeticholic acid to one another or placebo.
Siddharth Singh, Rohan Khera, Alina M. Allen, M. Hassan Murad, Rohit Loomba – 18 July 2015 – We performed a Bayesian network meta‐analysis combining direct and indirect treatment comparisons to assess the comparative effectiveness of pharmacological agents for the treatment of nonalcoholic steatohepatitis (NASH). Through systematic literature review, we identified nine randomized, controlled trials (RCTs) including 964 patients with biopsy‐proven NASH, comparing vitamin E, thiazolidinediones (TZDs), pentoxifylline, or obeticholic acid to one another or placebo.
Huey‐Huey Chua, Daw‐Jen Tsuei, Po‐Huang Lee, Yung‐Ming Jeng, Jean Lu, Jia‐Feng Wu, De‐Shiuan Su, Ya‐Hui Chen, Chin‐Sung Chien, Pei‐Chi Kao, Chien‐Nan Lee, Rey‐Heng Hu, Yen‐Hsuan Ni, Mei‐Hwei Chang – 16 July 2015 – Male predominance of hepatocellular carcinoma (HCC) occurs particularly among young children aged 6‐9 years, indicative of a possible role of the Y chromosome–encoded oncogene in addition to an androgenic effect.
Muhammed Yuksel, Yipeng Wang, Ningwen Tai, Jian Peng, Junhua Guo, Kathie Beland, Pascal Lapierre, Chella David, Fernando Alvarez, Isabelle Colle, Huiping Yan, Giorgina Mieli‐Vergani, Diego Vergani, Yun Ma, Li Wen – 16 July 2015 – Autoimmune hepatitis (AIH) in humans is a severe inflammatory liver disease characterized by interface hepatitis, the presence of circulating autoantibodies, and hyper‐gammaglobulinemia. There are two types of AIH, type 1 (AIH‐1) and type 2 (AIH‐2), characterized by distinct autoimmune serology.
Alessandro Vitale, Fabio Farinati, Patrizia Burra, Franco Trevisani, Edoardo G.
16 July 2015
Ezequiel Rodriguez, Gustavo Henrique Pereira, Elsa Solà, Chiara Elia, Rogelio Barreto, Elisa Pose, Jordi Colmenero, Javier Fernandez, Miquel Navasa, Vicente Arroyo, Pere Ginès – 15 July 2015 – There is little information on the effects of treatment with vasoconstrictors plus albumin in patients with type 2 hepatorenal syndrome (HRS), particularly those awaiting liver transplantation (LT). This study reports the effects of treatment of type 2 HRS in patients on the waiting list for LT. We included 56 patients with type 2 HRS who were awaiting LT.
Isobel Ramsay, Luke Snell, Vikram Sharma, James O'Beirne, David Patch, Aileen Marshall, Charles Imber, Samreen Ijaz, Dianne Irish, Rachel H. Westbrook – 15 July 2015