Ingrid Slaba, Jing Wang, Elzbieta Kolaczkowska, Braedon McDonald, Woo‐Yong Lee, Paul Kubes – 22 July 2015 – Although platelets have been extensively studied in hemostasis and inflammation, their role is not well understood in sterile liver injury and repair. Using a thermally induced focal liver injury and repair model and multichannel spinning disk confocal microscopy allowed visualization of the dynamic behavior of platelets and neutrophils in this insult.

Gregory J. Gores – 22 July 2015

Ingrid Slaba, Jing Wang, Elzbieta Kolaczkowska, Braedon McDonald, Woo‐Yong Lee, Paul Kubes – 22 July 2015 – Although platelets have been extensively studied in hemostasis and inflammation, their role is not well understood in sterile liver injury and repair. Using a thermally induced focal liver injury and repair model and multichannel spinning disk confocal microscopy allowed visualization of the dynamic behavior of platelets and neutrophils in this insult.

Joshua H. Wolf, Michael V. Holmes, Suomi Fouraschen, Brendan J. Keating, Talia Baker, Jean Emond, Daniel J. Rader, Abraham Shaked, Kim M. Olthoff – 22 July 2015 – Following living donor liver transplantation (LDLT; and unlike deceased donor liver transplantation [DDLT]), the liver must rapidly regenerate, and sometimes segmental graft dysfunction (SGD) is observed. Hepatic regeneration requires substantial de novo lipid synthesis, and we previously reported that expression of lipid‐related genes is dysregulated in LDLT.

Jin Woo Choi, Hwan Jun Jae, Hyo‐Cheol Kim, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh, Jin Wook Chung – 22 July 2015 – The purpose of our study was to address the long‐term outcome of angioplasty and stent placement for hepatic venous outflow obstruction following pediatric liver transplantation. From October 1999 to December 2011, 20 stenotic lesions were confirmed to constitute hepatic venous outflow obstruction in 18 pediatric patients (13 boys, 5 girls) among 152 pediatric patients following liver transplantation and were managed with endovascular intervention.

Roberto Scirpo, Romina Fiorotto, Ambra Villani, Mariangela Amenduni, Carlo Spirli, Mario Strazzabosco – 21 July 2015 – Cystic fibrosis–associated liver disease is a chronic cholangiopathy that negatively affects the quality of life of cystic fibrosis patients. In addition to reducing biliary chloride and bicarbonate secretion, up‐regulation of toll‐like receptor 4/nuclear factor kappa light‐chain‐enhancer of activated B cells (NF‐κB)–dependent immune mechanisms plays a major role in the pathogenesis of cystic fibrosis–associated liver disease and may represent a therapeutic target.

Yoshihiro Kamada, Masafumi Ono, Hideyuki Hyogo, Hideki Fujii, Yoshio Sumida, Kojiroh Mori, Saiyu Tanaka, Makoto Yamada, Maaya Akita, Kayo Mizutani, Hironobu Fujii, Akiko Yamamoto, Shinji Takamatsu, Yuichi Yoshida, Yoshito Itoh, Norifumi Kawada, Kazuaki Chayama, Toshiji Saibara, Tetsuo Takehara, Eiji Miyoshi – 21 July 2015 – Nonalcoholic fatty liver disease (NAFLD) is a growing medical problem; thus, discriminating nonalcoholic steatohepatitis (NASH) from NAFLD is of great clinical significance.

Siddharth Sood, Craig Haifer, Lijia Yu, Julie Pavlovic, Paul J. Gow, Robert M. Jones, Kumar Visvanathan, Peter W. Angus, Adam G. Testro – 20 July 2015 – Cytomegalovirus (CMV) can reactivate following liver transplantation. Management of patients currently considered low risk based on pretransplant serology remains contentious, with universal prophylaxis and preemptive strategies suffering from significant deficiencies.

Mamatha Bhat, Peter Ghali, Kathleen C. Rollet‐Kurhajec, Aparna Bhat, Philip Wong, Marc Deschenes, Giada Sebastiani – 20 July 2015 – Noninvasive serum fibrosis biomarkers predict clinical outcomes in pretransplant patients with chronic liver disease. We investigated the role of serum fibrosis biomarkers and of changes in biomarkers in predicting death and graft loss after liver transplantation (LT).

James Fung, Regina Lo, See‐Ching Chan, Kenneth Chok, Tiffany Wong, William Sharr, Tan‐To Cheung, Albert C. Y. Chan, Wing‐Chiu Dai, Sui‐Ling Sin, Irene Ng, Ching‐Lung Lai, Man‐Fung Yuen, Chung‐Mau Lo – 20 July 2015 – The outcomes of hepatitis B virus (HBV)–related hepatitis after liver transplantation (LT) without hepatitis B immune globulin (HBIG) is not well documented. This study aims to determine the outcomes of chronic hepatitis B (CHB) patients using an HBIG‐free regimen.