Author checklist
27 January 2016
ISSN
27 January 2016
Table of contents
27 January 2016
Editorial board
27 January 2016
Instructions to authors
27 January 2016
Meeting notices
27 January 2016
Variceal Hemorrhage in a Patient With Hepatitis C Virus Cirrhosis in Whom Liver Synthetic Function had Normalized After Viral Elimination
Jordan Sack, Guadalupe Garcia‐Tsao – 25 January 2016
Challenge accepted: Confronting readmissions for our patients with cirrhosis
Elliot B. Tapper – 25 January 2016
Variceal Hemorrhage in a Patient With Hepatitis C Virus Cirrhosis in Whom Liver Synthetic Function had Normalized After Viral Elimination
Jordan Sack, Guadalupe Garcia‐Tsao – 25 January 2016
Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice
Yuanyuan Li, Munaf Zalzala, Kavita Jadhav, Yang Xu, Takhar Kasumov, Liya Yin, Yanqiao Zhang – 25 January 2016 – Nonalcoholic fatty liver disease (NAFLD) is a common liver disease that ranges from simple steatosis to nonalcoholic steatohepatitis (NASH). So far, the underlying mechanism remains poorly understood. Here, we show that hepatic carboxylesterase 2 (CES2) is markedly reduced in NASH patients, diabetic db/db mice, and high‐fat diet (HFD)‐fed mice. Restoration of hepatic CES2 expression in db/db or HFD‐fed mice markedly ameliorates liver steatosis and insulin resistance.