World‐wide relative contribution of hepatitis B and C viruses in hepatocellular carcinoma
Catherine de Martel, Delphine Maucort‐Boulch, Martyn Plummer, Silvia Franceschi – 3 July 2015 – Hepatitis B virus (HBV) and hepatitis C virus (HCV) are major causes of hepatocellular carcinoma (HCC). In order to assess the relative contribution of HBV and HCV to HCC worldwide, and identify changes over time, we conducted a systematic review of case series published up to the year 2014. Eligible studies had to report seroprevalence of both hepatitis B surface antigen (HBsAg) and antibodies to HCV (anti‐HCV), alone and in combination, for at least 20 adult HCC cases.