Ramesh Kudira, Thomas Malinka, Andreas Kohler, Michel Dosch, Mercedes Gomez de Agüero, Nicolas Melin, Stefanie Haegele, Patrick Starlinger, Niran Maharjan, Smita Saxena, Adrian Keogh, Deborah Stroka, Daniel Candinas, Guido Beldi – 8 February 2016 – Paracrine signalling mediated by cytokine secretion is essential for liver regeneration after hepatic resection, yet the mechanisms of cellular crosstalk between immune and parenchymal cells are still elusive. Interleukin‐22 (IL‐22) is released by immune cells and mediates strong hepatoprotective functions.

Nam‐On Ku, Pavel Strnad, Heike Bantel, M. Bishr Omary – 8 February 2016 – Keratins, formerly known as cytokeratins, are the major epithelial‐specific subgroup of intermediate filament proteins. Adult hepatocytes express keratin polypeptides 8 and 18 (K8/K18), whereas cholangiocytes express K8/K18 and keratins 7 and 19 (K7/K19). Keratins function primarily to protect hepatocytes from apoptosis and necrosis, which was revealed using several genetic mouse models.

Christophe Hézode, Stéphane Chevaliez, Giovanna Scoazec, Alexandre Soulier, Anne Varaut, Magali Bouvier‐Alias, Isaac Ruiz, Françoise Roudot‐Thoraval, Ariane Mallat, Cyrille Féray, Jean‐Michel Pawlotsky – 8 February 2016 – Failure to achieve sustained virological response (SVR) with hepatitis C virus (HCV) direct‐acting antiviral‐based regimens is commonly associated with emergence of resistance‐associated variants (RAVs).

Brett D. Lindenbach – 8 February 2016

Sung‐Hoon Kim, Young‐Jin Moon, Sooho Lee, Sung‐Moon Jeong, Jun‐Gol Song, Gyu‐Sam Hwang – 6 February 2016 – Hemodynamic perturbation during hepatic graft reperfusion in patients undergoing liver transplantation (LT) is challenging and is frequently accompanied by bradyarrhythmia and even asystole. However, detailed data on electrocardiographic (ECG) changes during reperfusion are almost nonexistent, although the correct diagnosis by record is important for the treatment. We aimed to identify ECG rhythm disturbances during graft reperfusion and to investigate risk factors and outcomes.

Amy G. Feldman, Katie Neighbors, Shubhra Mukherjee, Melanie Rak, James W. Varni, Estella M. Alonso – 6 February 2016 – The purpose of this article is to investigate the spectrum of physical function of pediatric liver transplantation (LT) recipients 12‐24 months after LT. Review data were collected through the functional outcomes group, an ancillary study of the Studies of Pediatric Liver Transplantation registry. Patients were eligible if they had survived LT by 12‐24 months.

Daisuke Ito, Nobuhisa Akamatsu, Akihiko Ichida, Junichi Kaneko, Junichi Arita, Kiyoshi Hasegawa, Yoshihiro Sakamoto, Norihiro Kokudo – 6 February 2016

Carla Venturi, Raymond Reding, Jorge Abarca Quinones, Etienne Sokal, Jacques Rahier, Javier Bueno, Christine Sempoux – 6 February 2016 – Activated hepatic stellate cells (HSCs) are the main collagen‐producing cells in liver fibrogenesis. With the purpose of analyzing their presence and relevance in predicting liver allograft fibrosis development, 162 liver biopsies of 54 pediatric liver transplantation (LT) recipients were assessed at 6 months, 3 years, and 7 years after LT.

Andres F. Carrion – 6 February 2016

Hung‐Tien Kuo, Erik Lum, Paul Martin, Suphamai Bunnapradist – 6 February 2016 – The effects of diabetic status and acute rejection (AR) on liver transplant outcomes are largely unknown. We studied 13,736 liver recipients from the United Network for Organ Sharing/Organ Procurement Transplant Network database who underwent transplantation between 2004 and 2007 with a functioning graft for greater than 1 year.