Myeloid cells in hepatocellular carcinoma

Shanshan Wan, Ning Kuo, Ilona Kryczek, Weiping Zou, Theodore H. Welling – 24 April 2015 – Hepatocellular carcinoma (HCC) is highly associated with inflammation. Myeloid cells, including tumor‐associated macrophages and myeloid‐derived suppressor cells, are abundant in the HCC microenvironment and are often associated with poor prognosis. Myeloid cells in HCC play a vital role in supporting tumor initiation, progression, angiogenesis, metastasis, and therapeutic resistance.

Impact of clinically evident portal hypertension on the course of hepatocellular carcinoma in patients listed for liver transplantation

François Faitot, Marc‐Antoine Allard, Gabriella Pittau, Oriana Ciacio, René Adam, Denis Castaing, Antonio Sa Cunha, Gilles Pelletier, Daniel Cherqui, Didier Samuel, Eric Vibert – 24 April 2015 – Liver transplantation (LT) is the best curative treatment for early hepatocellular carcinoma (HCC) in patients with cirrhosis. However, the current shortage of organs causes prolonged waiting times and poorer intention‐to‐treat (ITT) survival (i.e., after listing) owing to tumor progression and dropout.

Subscribe to