Portal inflammation is independently associated with fibrosis and metabolic syndrome in pediatric nonalcoholic fatty liver disease
Jake P. Mann, Rita De Vito, Antonella Mosca, Anna Alisi, Matthew J. Armstrong, Massimiliano Raponi, Ulrich Baumann, Valerio Nobili – 5 December 2015 – Pediatric nonalcoholic fatty liver disease (NAFLD) histology demonstrates variable amounts of portal inflammation, which may be associated with more severe liver disease and fibrosis. We assessed the relationship between portal inflammation, hepatic fibrosis, and the metabolic syndrome in pediatric NAFLD. Children with biopsy‐proven NAFLD were eligible for inclusion.