Temoporfin improves efficacy of photodynamic therapy in advanced biliary tract carcinoma: A multicenter prospective phase II study

Andrej Wagner, Ulrike W. Denzer, Daniel Neureiter, Tobias Kiesslich, Andreas Puespoeck, Erik A.J. Rauws, Klaus Emmanuel, Nora Degenhardt, Ulrich Frick, Ulrich Beuers, Ansgar W. Lohse, Frieder Berr, Gernot W. Wolkersdörfer – 20 May 2015 – Photodynamic therapy using porfimer (P‐PDT) improves palliation and survival in nonresectable hilar bile duct cancer. Tumoricidal penetration depth of temoporfin‐PDT (T‐PDT) is twice that of P‐PDT. In a single‐arm phase II study we investigated the safety, efficacy, survival time, and adverse events of T‐PDT compared with previous data on P‐PDT.

A multicenter study of 30 days complications after deceased donor liver transplantation in the model for end‐stage liver disease score era

Anup Parikh, Kenneth W. Washburn, Lea Matsuoka, Urvashi Pandit, Jennifer E. Kim, Jose Almeda, Cesar Mora‐Esteves, Glenn Halff, Yuri Genyk, Bart Holland, Dorian J. Wilson, Linda Sher, Baburao Koneru – 19 May 2015 – Knowledge of risk factors for posttransplant complications is likely to improve patient outcomes. Few large studies of all early postoperative complications after deceased donor liver transplantation (DDLT) exist. Therefore, we conducted a retrospective, cohort study of 30‐day complications, their risk factors, and the impact on outcomes after DDLT.

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Susan Holtzman, Hance A. Clarke, Stuart A. McCluskey, Kara Turcotte, David Grant, Joel Katz – 19 May 2015

Liver sharing and organ procurement organization performance under redistricted allocation

Sommer E. Gentry, Eric K. H. Chow, Allan Massie, Xun Luo, Eugene Shteyn, Joshua Pyke, David Zaun, Jon J. Snyder, Ajay K. Israni, Bert Kasiske, Dorry L. Segev – 19 May 2015 – Concerns have been raised that optimized redistricting of liver allocation areas might have the unintended result of shifting livers from better‐performing to poorer‐performing organ procurement organizations (OPOs). We used liver simulated allocation modeling to simulate a 5‐year period of liver sharing within either 4 or 8 optimized districts.

Biliary complications in pediatric liver transplantation: Incidence and management over a decade

Jerome M. Laurence, Gonzalo Sapisochin, Maria DeAngelis, John B. Seal, Mar M. Miserachs, Max Marquez, Murtuza Zair, Annie Fecteau, Nicola Jones, Alexander Hrycko, Yaron Avitzur, Simon C. Ling, Vicky Ng, Mark Cattral, David Grant, Binita M. Kamath, Anand Ghanekar – 19 May 2015 – This study analyzed how features of a liver graft and the technique of biliary reconstruction interact to affect biliary complications in pediatric liver transplantation. A retrospective analysis was performed of data collected from 2001 to 2011 in a single high‐volume North American pediatric transplant center.

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