Resminostat: Opening the door to epigenetic treatments for liver cancer
Jun Zhao, Matthew W. Lawless – 18 April 2015
Value anti–hepatitis C virus therapy by its clinical efficacy
Adriaan J. van der Meer – 18 April 2015
GNPAT Variant associated with severe iron overload in HFE hemochromatosis
Edouard Bardou‐Jacquet, Marie de Tayrac, Jean Mosser, Yves Deugnier – 18 April 2015
Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury
Daniel J. Antoine, Venkata S. Sabbisetti, Ben Francis, Andrea L. Jorgensen, Darren G.N. Craig, Kenneth J. Simpson, Joseph V. Bonventre, B. Kevin Park, James W. Dear – 18 April 2015 – Acute kidney injury in the context of acetaminophen (APAP; paracetamol)‐induced liver injury is an important predictor of the requirement for urgent liver transplantation (LT) to avoid death. However, the prognostic biomarker used to report kidney dysfunction (serum creatinine concentration) has suboptimal sensitivity and specificity.
Does IL‐22 protect against liver fibrosis in hepatitis C virus infection?
Liyuan Wu, Jingmin Zhao – 18 April 2015
Alcoholic hepatitis: Can we outwit the Grim Reaper?
Sakkarin Chirapongsathorn, Patrick S. Kamath, Vijay Shah – 18 April 2015
The travails of setting up a living donor liver transplant program: Experience from Pakistan and lessons learned
Faisal Saud Dar, Abu Bakar Hafeez Bhatti, Abdul‐Wahab Dogar, Haseeb Zia, Sadaf Amin, Atif Rana, Rashid Nazer, Nasir Ayub Khan, Etizaz‐ud‐din Khan, Muhammad Zameer Rajput, Muhammad Salih, Najmul Hassan Shah – 17 April 2015 – Living donor liver transplantation (LDLT) is the only treatment option for patients with end‐stage liver disease (ESLD) where cadaveric donors are not available. In developing countries, the inception of LDLT programs remains a challenge. The first successful liver transplantation program in Pakistan started transplantation in 2012.
The friendly incidental portal vein thrombus in liver transplantation
Peng Soon Koh, See Ching Chan, Kenneth Siu‐Ho Chok, William Wei Sharr, Tiffany Cho-Lam Wong, Sui Ling Sin, Chung Mau Lo – 17 April 2015 – Improved outcomes have been shown in liver transplantation (LT) with portal vein thrombosis (PVT). However, PVT is still discovered incidentally during surgery despite careful preoperative imaging. Data are limited comparing the outcomes of incidental PVT with PVT diagnosed via preoperative imaging before LT. This study aims to compare the overall outcomes of patients with PVT.
Recipient factors associated with having a potential living donor for liver transplantation
Adam Doyle, Rania N. Rabie, Arastoo Mokhtari, Mark Cattral, Anand Ghanekar, David Grant, Paul Greig, Gary Levy, Leslie Lilly, Ian McGilvray, Markus Selzner, Nazia Selzner, Eberhard L. Renner – 17 April 2015 – Because of a persistent discrepancy between the demand for liver transplantation (LT) and the supply of deceased donor organs, there is an interest in increasing living donation rates at centers trained in this method of transplantation. We examined a large socioeconomically heterogeneous cohort of patients listed for LT to identify recipient factors associated with living donation.
Cardiovascular disease after liver transplantation: When, What, and Who Is at Risk
Lynn A. Fussner, Julie K. Heimbach, Chun Fan, Ross Dierkhising, Elizabeth Coss, Michael D. Leise, Kymberly D. Watt – 16 April 2015 – The evolution of metabolic and cardiovascular disease (CVD) complications after liver transplantation (LT) is poorly characterized. We aim to illustrate the prevalence of obesity and metabolic syndrome (MS), define the cumulative incidence of CVD, and characterize risk factors associated with these comorbidities after LT. A retrospective review of 455 consecutive LT recipients from 1999 to 2004 with an 8‐ to 12‐year follow‐up was performed.