K. Rajender Reddy, Marc Bourlière, Mark Sulkowski, Masao Omata, Stefan Zeuzem, Jordan J. Feld, Eric Lawitz, Patrick Marcellin, Tania M. Welzel, Robert Hyland, Xiao Ding, Jenny Yang, Steven Knox, Phillip Pang, Hadas Dvory‐Sobol, G. Mani Subramanian, William Symonds, John G. McHutchison, Alessandra Mangia, Edward Gane, Masashi Mizokami, Stanislas Pol, Nezam Afdhal – 4 April 2015 – Patients with hepatitis C virus (HCV) infection and cirrhosis are underrepresented in clinical trials of interferon‐free regimens of direct‐acting antiviral agents, making it difficult to optimize therapy.

Sharat Varma, Nicole Revencu, Xavier Stephenne, Isabelle Scheers, Françoise Smets, Ana Beleza‐Meireles, Raymond Reding, Tania Roskams, Etienne M. Sokal – 4 April 2015 – We investigated predictors of clinical evolution in progressive familial intrahepatic cholestasis type 2 patients and how they relate to bile salt export pump (BSEP) expression and its (re)targeting. Our retrospective study included 22 children with progressive familial intrahepatic cholestasis type 2.

3 April 2015

3 April 2015

Neehar D. Parikh, David Hutton, Wesley Marrero, Kunal Sanghani, Yongcai Xu, Mariel Lavieri – 3 April 2015 – With the aging US population, demographic shifts, and obesity epidemic, there is potential for further exacerbation of the current liver donor shortage. We aimed to project the availability of liver grafts in the United States.

Christopher Lee, Lauren Ihde, Andrew Kim, Idoia Santos, Lea Matsuoka, Yong Cen, Melissa Wallman, Edward Grant – 2 April 2015 – No guidelines exist for the management of pulmonary nodules in patients with hepatocellular carcinoma (HCC) who are being evaluated for liver transplantation. The 172 patients with HCC who were listed for liver transplant at our institution received both pretransplant chest computed tomography (CT) and follow‐up CT.

Joao Seda Neto, Flávia H. Feier, Ana Luiza Bierrenbach, Cristiana M. Toscano, Eduardo A. Fonseca, Renata Pugliese, Helry L. Candido, Marcel R. Benavides, Gilda Porta, Paulo Chapchap – 2 April 2015 – Biliary atresia (BA) is the main diagnosis leading to liver transplantation (LT) in children. When diagnosed early in life, a Kasai portoenterostomy (Kasai‐PE) can prevent or postpone LT. Instances of previous operations can result in difficulties during the LT. We hypothesized that a previous Kasai‐PE could affect LT outcomes.

J. Michael Millis – 2 April 2015

Jonathan G. Stine, Neeral L. Shah, Curtis K. Argo, Shawn J. Pelletier, Stephen H. Caldwell, Patrick G. Northup – 2 April 2015 – Portal vein thrombosis (PVT) is a common complication of cirrhosis sometimes implicated in hepatic decompensation. There are no consistent epidemiologic data to suggest an increased risk of thrombotic complications in nonalcoholic steatohepatitis (NASH); however, research suggests an increased risk of thrombosis.

David Wyles, Paul Pockros, Giuseppe Morelli, Ziad Younes, Evguenia Svarovskaia, Jenny C. Yang, Phillip S. Pang, Yanni Zhu, John G. McHutchison, Steven Flamm, Eric Lawitz – 2 April 2015 – Patients who fail to achieve sustained virological response (SVR) after treatment with sofosbuvir (SOF) plus ribavirin (RBV) with or without pegylated interferon (Peg‐IFN) do not have established retreatment options.